Outer membrane vesicle vaccines

F Micoli, CA MacLennan - Seminars in immunology, 2020 - Elsevier
Abstract Outer Membrane Vesicles (OMV) have received increased attention in recent years
as a vaccine platform against bacterial pathogens. OMV from Neisseria meningitidis …

Insights into the structure of Escherichia coli outer membrane as the target for engineering microbial cell factories

J Wang, W Ma, X Wang - Microbial Cell Factories, 2021 - Springer
Escherichia coli is generally used as model bacteria to define microbial cell factories for
many products and to investigate regulation mechanisms. E. coli exhibits phospholipids …

Emergence of plasmid-mediated colistin resistance mechanism MCR-1 in animals and human beings in China: a microbiological and molecular biological study

YY Liu, Y Wang, TR Walsh, LX Yi, R Zhang… - The Lancet infectious …, 2016 - thelancet.com
Background Until now, polymyxin resistance has involved chromosomal mutations but has
never been reported via horizontal gene transfer. During a routine surveillance project on …

Novel Odoribacter splanchnicus Strain and Its Outer Membrane Vesicles Exert Immunoregulatory Effects in vitro

K Hiippala, G Barreto, C Burrello… - Frontiers in …, 2020 - frontiersin.org
Odoribacter splanchnicus, belonging to the order Bacteroidales, is a common, short-chain
fatty acid producing member of the human intestinal microbiota. A decreased abundance of …

Mucosal Prevalence and Interactions with the Epithelium Indicate Commensalism of Sutterella spp.

K Hiippala, V Kainulainen, M Kalliomäki… - Frontiers in …, 2016 - frontiersin.org
Sutterella species have been frequently associated with human diseases, such as autism,
Down syndrome, and inflammatory bowel disease (IBD), but the impact of these bacteria on …

Outer membrane vesicle vaccine platforms

F Micoli, R Adamo, U Nakakana - BioDrugs, 2024 - Springer
Outer membrane vesicles (OMVs) are spontaneously released by many gram-negative
bacteria during their growth and constitute an important virulence factor for bacteria, hel** …

Influence of Core Oligosaccharide of Lipopolysaccharide to Outer Membrane Behavior of Escherichia coli

Z Wang, J Wang, G Ren, Y Li, X Wang - Marine drugs, 2015 - mdpi.com
Lipopolysaccharides, major molecules in the outer membrane of Gram-negative bacteria,
play important roles on membrane integrity of the cell. However, how the core …

Kdo2‐lipid A: structural diversity and impact on immunopharmacology

X Wang, PJ Quinn, A Yan - Biological Reviews, 2015 - Wiley Online Library
deoxy‐d‐manno‐octulosonic acid‐lipid A (Kdo2‐lipid A) is the essential component of
lipopolysaccharide in most Gram‐negative bacteria and the minimal structural component to …

Microbial biosynthesis of designer outer membrane vesicles

JL Baker, L Chen, JA Rosenthal, D Putnam… - Current opinion in …, 2014 - Elsevier
Highlights•Bacterial outer membrane vesicles (OMVs) can be rationally engineered for
biotechnological applications.•OMV production can be increased by manipulating cell …

Cell-Free Supernatant of Odoribacter splanchnicus Isolated From Human Feces Exhibits Anti-colorectal Cancer Activity

BS Oh, WJ Choi, JS Kim, SW Ryu, SY Yu… - Frontiers in …, 2021 - frontiersin.org
The gut microbiota (GM) has been shown to be closely associated with the development of
colorectal cancer (CRC). However, the involvement of GM is CRC has mainly been …