An unusual light-sensing function for coenzyme B12 in bacterial transcription regulator CarH

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Redox driven B12-ligand switch drives CarH photoresponse

H Poddar, R Rios-Santacruz, DJ Heyes… - Nature …, 2023 - nature.com
CarH is a coenzyme B12-dependent photoreceptor involved in regulating carotenoid
biosynthesis. How light-triggered cleavage of the B12 Co-C bond culminates in CarH …
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Photocobilins integrate B12 and bilin photochemistry for enzyme control

S Zhang, LN Jeffreys, H Poddar, Y Yu, C Liu… - Nature …, 2024 - nature.com
Photoreceptor proteins utilise chromophores to sense light and trigger a biological
response. The discovery that adenosylcobalamin (or coenzyme B12) can act as a light …
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Organic dyes in optogenetics

A Penzkofer, P Hegemann… - Organic Lasers and …, 2024 - iopscience.iop.org
This chapter is an authoritative and extensive review on the use of organic dyes in the new
and exciting field of optogenetics. The authors begin by outlining the essence of …
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