Epithelial cells form tight barriers that line both the outer and inner surfaces of organs and
cavities and therefore face diverse environmental challenges. The response to these …

Numerous cell functions are accompanied by phenotypic changes in viscoelastic properties,
and measuring them can help elucidate higher level cellular functions in health and disease …

Cells exist in different phenotypes and can transition between them. A phenotype may be
characterized by many different aspects. Here, we focus on the example of whether the cell …

Cell transitions between the epithelial and mesenchymal phenotypes provide the regulated
morphogenesis and regeneration throughout the ontogenesis. The tissue mechanics and …

In healthy tissues, cells are in mechanical homeostasis. During cancer progression, this
equilibrium is disrupted. Cancer cells alter their mechanical phenotype to a softer and more …

AFM-based force–distance curves are commonly used to characterize the nanomechanical
properties of live cells. The transformation of these curves into nanomechanical properties …

The viscoelastic parameters of the cell can report on the cell state, cellular processes and
diseases. Cell mechanics strongly rely on the properties of the cytoskeleton, an important …

Mechanochemical simulations of actomyosin networks are traditionally based on one-
dimensional models of actin filaments having zero width. Here, and in the follow up paper …

The biophysical properties of cells described at the level of whole cells or their membranes
have many consequences for their biological behavior. However, our understanding of the …

Cortical formins, pivotal for the assembly of linear actin filaments beneath the membrane,
exert only minor effects on unconfined cell migration of weakly and moderately adherent …