Drug designing and development is an important area of research for pharmaceutical
companies and chemical scientists. However, low efficacy, off-target delivery, time …

Neurodegenerative diseases (NDDs) are incurable and debilitating conditions that result in
progressive degeneration and/or death of nerve cells in the central nervous system (CNS) …

The accumulation of abnormal protein aggregates represents a universal hallmark of
neurodegenerative diseases (NDDs). Post-translational modifications (PTMs) regulate …

Background: Recent studies had explored that gut microbiota was associated with
neurodegenerative diseases (including Alzheimer's disease (AD), Parkinson's disease (PD) …

Autophagy is an important cellular self-digestion and recycling pathway that helps in
maintaining cellular homeostasis. Dysregulation at various steps of the autophagic and …

In the past two decades, advances in sequencing technology and analysis of the human and
mouse genome have led to the discovery of many non-protein-coding RNAs (ncRNAs) …

Over thousands of years, natural bioactive compounds derived from plants (bioactive
phytocompounds, BPCs) have been used worldwide to address human health issues …

Neurodegenerative diseases are severely debilitating conditions characterized primarily by
progressive neuronal loss and impairment of the nervous system. Alzheimer's and …

Being characterized by progressive and severe damage in neuronal cells,
neurodegenerative diseases (NDDs) are the major cause of disability and morbidity in the …

Alzheimer's is one of the fast-growing diseases among people worldwide leading to brain
atrophy. Neuroimaging reveals extensive information about the brain's anatomy and …