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[HTML][HTML] PRIMUS: rapid reconstruction of pedigrees from genome-wide estimates of identity by descent
Understanding and correctly utilizing relatedness among samples is essential for genetic
analysis; however, managing sample records and pedigrees can often be error prone and …
analysis; however, managing sample records and pedigrees can often be error prone and …
Phylogenomics from low‐coverage whole‐genome sequencing
Phylogenetic studies are increasingly reliant on next‐generation sequencing.
Transcriptomic and hybrid enrichment sequencing techniques remain the most prevalent …
Transcriptomic and hybrid enrichment sequencing techniques remain the most prevalent …
Optimal sequencing depth design for whole genome re-sequencing in pigs
Background As whole-genome sequencing is becoming a routine technique, it is important
to identify a cost-effective depth of sequencing for such studies. However, the relationship …
to identify a cost-effective depth of sequencing for such studies. However, the relationship …
An evaluation of sequencing coverage and genoty** strategies to assess neutral and adaptive diversity
Whole genome sequences (WGS) greatly increase our ability to precisely infer population
genetic parameters, demographic processes, and selection signatures. However, WGS may …
genetic parameters, demographic processes, and selection signatures. However, WGS may …
Genetic factors associated with suicidal behaviors and alcohol use disorders in an American Indian population
American Indians (AI) demonstrate the highest rates of both suicidal behaviors (SB) and
alcohol use disorders (AUD) among all ethnic groups in the US. Rates of suicide and AUD …
alcohol use disorders (AUD) among all ethnic groups in the US. Rates of suicide and AUD …
Deep whole-genome sequencing of 90 Han Chinese genomes
Next-generation sequencing provides a high-resolution insight into human genetic
information. However, the focus of previous studies has primarily been on low-coverage …
information. However, the focus of previous studies has primarily been on low-coverage …
Genetic loci for alcohol-related life events and substance-induced affective symptoms: indexing the “dark side” of addiction
A limited number of genetic variants have been identified in traditional GWAS as risk or
protective factors for alcohol use disorders (AUD) and related phenotypes. We herein report …
protective factors for alcohol use disorders (AUD) and related phenotypes. We herein report …
Testing rare-variant association without calling genotypes allows for systematic differences in sequencing between cases and controls
Next-generation sequencing of DNA provides an unprecedented opportunity to discover
rare genetic variants associated with complex diseases and traits. However, the common …
rare genetic variants associated with complex diseases and traits. However, the common …
A bioinformatic platform to integrate target capture and whole genome sequences of various read depths for phylogenomics
The increasing availability of short‐read whole genome sequencing (WGS) provides
unprecedented opportunities to study ecological and evolutionary processes. Although loci …
unprecedented opportunities to study ecological and evolutionary processes. Although loci …
Whole genome sequence study of cannabis dependence in two independent cohorts
Recent advances in genome wide sequencing techniques and analytical methods allow for
more comprehensive examinations of the genome than microarray‐based genome‐wide …
more comprehensive examinations of the genome than microarray‐based genome‐wide …