Copper: an intracellular achilles' heel allowing the targeting of epigenetics, kinase pathways, and cell metabolism in cancer therapeutics

F Michniewicz, F Saletta, JRC Rouaen… - …, 2021 - Wiley Online Library
Copper is an essential transition metal frequently increased in cancer known to strongly
influence essential cellular processes. Targeted therapy protocols utilizing both novel and …

Mo (W, V) Cu (Ag) S (Se) cluster compounds

HW Hou, XQ **n, S Shi - Coordination Chemistry Reviews, 1996 - Elsevier
This review summarizes the preparation, skeletal structure, reactions, spectroscopic
properties and non-linear optical properties of Mo (W, V) Cu (Ag) S (Se) cluster …

Substituent Effect to Fine‐Tune Energy Levels of Atom‐Precise [MoOS3]2− Modified Copper(I) Thiolate Clusters Boosting Recyclable Photocatalysis

YD Cao, D Yin, S Li, XY Dong, Y Feng… - Angewandte Chemie …, 2023 - Wiley Online Library
The propulsion of photocatalytic hydrogen (H2) production is limited by the rational design
and regulation of catalysts with precise structures and excellent activities. In this work, the …

AW/Cu synthetic model for the Mo/Cu cofactor of aerobic CODH indicates that biochemical CO oxidation requires a frustrated Lewis acid/base pair

D Ghosh, S Sinhababu, BD Santarsiero… - Journal of the …, 2020 - ACS Publications
Constructing synthetic models of the Mo/Cu active site of aerobic carbon monoxide
dehydrogenase (CODH) has been a long-standing synthetic challenge thought to be crucial …

Diverse biological roles of the tetrathiomolybdate anion

BK Maiti, JJG Moura - Coordination Chemistry Reviews, 2021 - Elsevier
Biological systems use proteins as scaffolds to harbor catalytic metal centers responsible for
the assimilatory and energy pathways that make life possible. Therefore, metal homeostasis …

Degradable organically-derivatized polyoxometalate with enhanced activity against glioblastoma cell line

S She, S Bian, R Huo, K Chen, Z Huang, J Zhang… - Scientific reports, 2016 - nature.com
High efficacy and low toxicity are critical for cancer treatment. Polyoxometalates (POMs)
have been reported as potential candidates for cancer therapy. On accounts of the slow …

Syntheses, structures, and reactions of binary and tertiary thiomolybdate complexes containing the (O) Mo (Sx) and (S) Mo (Sx) functional groups (x= 1, 2, 4)

D Coucouvanis - Advances in Inorganic Chemistry, 1998 - Elsevier
Publisher Summary This chapter discusses syntheses, structures, and reactions of binary
and tertiary thiomolybdate complexes containing the (O) Mo (Sx,) and (S) Mo (Sx,) functional …

Bioinorganic modeling chemistry of carbon monoxide dehydrogenases: description of model complexes, current status and possible future scopes

A Majumdar - Dalton Transactions, 2014 - pubs.rsc.org
Carbon monoxide dehydrogenases (CODHs) use CO as their sole source of carbon and
energy and are found in both aerobic and anaerobic carboxidotrophic bacteria. Reversible …

Reactions of monodithiolene tungsten (VI) sulfido complexes with copper (I) in relation to the structure of the active site of carbon monoxide dehydrogenase

S Groysman, A Majumdar, SL Zheng… - Inorganic …, 2010 - ACS Publications
Reactions directed at the synthesis of structural analogues of the active site of molybdenum-
containing carbon monoxide dehydrogenase have been investigated utilizing [WO2S (bdt)] …

Low temperature solid-state reactions of (NH4) 2 [MS4](M= W, Mo) with [Cu (CH3CN) 4](PF6) and CuBr in the presence of Bis (diphenylphosphino) methane (dppm) …

JP Lang, K Tatsumi - Inorganic Chemistry, 1998 - ACS Publications
The solid-state reactions of (NH4) 2 [MS4](M= W, Mo),[Cu (CH3CN) 4](PF6), and bis
(diphenylphosphino) methane (dppm) at 110° C produced pentanuclear clusters [MS4Cu4 …