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Re-emerging concepts of immune dysregulation in autism spectrum disorders
A Erbescu, SM Papuc, M Budisteanu, A Arghir… - Frontiers in …, 2022 - frontiersin.org
Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by
communication and social interaction deficits, and by restricted interests and stereotyped …
communication and social interaction deficits, and by restricted interests and stereotyped …
Neuroimmune transcriptome changes in patient brains of psychiatric and neurological disorders
Y Chen, J Dai, L Tang, T Mikhailova, Q Liang, M Li… - Molecular …, 2023 - nature.com
Neuroinflammation has been implicated in multiple brain disorders but the extent and the
magnitude of change in immune-related genes (IRGs) across distinct brain disorders has not …
magnitude of change in immune-related genes (IRGs) across distinct brain disorders has not …
Brain exosomes as minuscule information hub for Autism Spectrum Disorder
DD Dean, S Agarwal, S Muthuswamy… - Expert Review of …, 2021 - Taylor & Francis
Introduction Autism spectrum disorder (ASD) is a neurodevelopmental disorder initiating in
the first three years of life. Early initiation of management therapies can significantly improve …
the first three years of life. Early initiation of management therapies can significantly improve …
Neonatal immune signatures differ by sex regardless of neurodevelopmental disorder status: Macrophage migration inhibitory factor (MIF) alone reveals a sex by …
Immune dysregulation, including aberrant peripheral cytokine/chemokine levels, is
implicated in neurodevelopmental disorders (NDD) such as autism spectrum disorder …
implicated in neurodevelopmental disorders (NDD) such as autism spectrum disorder …
Establishment of a schizophrenia classifier based on peripheral blood signatures and investigation of pathogenic miRNA-mRNA regulation
M **, Y Liu, G Hu, X Li, N Jia, X Cui, Z Li, L Ai… - Journal of Psychiatric …, 2023 - Elsevier
To date, the diagnosis of schizophrenia (SCZ) mainly relies on patients' or guardians' self-
reports and clinical observation, and the pathogenesis of SCZ remains elusive. In this study …
reports and clinical observation, and the pathogenesis of SCZ remains elusive. In this study …
[HTML][HTML] Sex-Differential Gene Expression in Develo** Human Cortex and Its Intersection With Autism Risk Pathways
Background Sex-differential biology may contribute to the consistently male-biased
prevalence of autism spectrum disorder (ASD). Gene expression differences between males …
prevalence of autism spectrum disorder (ASD). Gene expression differences between males …
MiR-15b-5p expression in the peripheral blood: a potential diagnostic biomarker of autism spectrum disorder
R Hosokawa, Y Yoshino, Y Funahashi, F Horiuchi… - Brain sciences, 2022 - mdpi.com
Background: Autism spectrum disorder (ASD), is a neurodevelopmental disorder that is
known to have a high degree of heritability. Diagnosis of ASD is difficult because of the high …
known to have a high degree of heritability. Diagnosis of ASD is difficult because of the high …
A meta-analysis of differentially expressed and regulatory genes with their functional enrichment analysis for brain transcriptome data in autism spectrum disorder
Autism spectrum disorder (ASD) is a complex neurodevelopmental condition characterized
by persistent challenges in social interactions and repetitive behavioral patterns. It is a …
by persistent challenges in social interactions and repetitive behavioral patterns. It is a …
Integrative functional genomic analysis in multiplex autism families from Kazakhstan
A Perfilyeva, K Bespalova, Y Perfilyeva… - Disease …, 2022 - Wiley Online Library
The study of extended pedigrees containing autism spectrum disorder‐(ASD‐) related
broader autism phenotypes (BAP) offers a promising approach to the search for ASD …
broader autism phenotypes (BAP) offers a promising approach to the search for ASD …
[HTML][HTML] Blood RNA Sequencing Indicates Upregulated BATF2 and LY6E and Downregulated ISG15 and MT2A Expression in Children with Autism Spectrum …
Mutations in over 100 genes are implicated in autism spectrum disorder (ASD). DNA SNPs,
CNVs, and epigenomic modifications also contribute to ASD. Transcriptomics analysis of …
CNVs, and epigenomic modifications also contribute to ASD. Transcriptomics analysis of …