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A Chemoselective Polarity‐Mismatched Photocatalytic C(sp3)−C(sp2) Cross‐Coupling Enabled by Synergistic Boron Activation**
J Brals, TM McGuire, AJB Watson - … Chemie International Edition, 2023 - Wiley Online Library
We report the development of a C (sp3)− C (sp2) coupling reaction using styrene boronic
acids and redox‐active esters under photoredox catalysis. The reaction proceeds through …
acids and redox‐active esters under photoredox catalysis. The reaction proceeds through …
Opening the HIV envelope: potential of CD4 mimics as multifunctional HIV entry inhibitors
A Laumaea, AB Smith III, J Sodroski… - Current Opinion in HIV …, 2020 - journals.lww.com
Close to 2 million individuals globally become infected with HIV-1 each year and just over
two-thirds will have access to life-prolonging antivirals. However, the rapid development of …
two-thirds will have access to life-prolonging antivirals. However, the rapid development of …
Piperidine CD4-mimetic compounds expose vulnerable Env epitopes sensitizing HIV-1-infected cells to ADCC
The ability of the HIV-1 accessory proteins Nef and Vpu to decrease CD4 levels contributes
to the protection of infected cells from antibody-dependent cellular cytotoxicity (ADCC) by …
to the protection of infected cells from antibody-dependent cellular cytotoxicity (ADCC) by …
Recent research results have converted gp120 binders to a therapeutic option for the treatment of HIV-1 infection. A medicinal chemistry point of view
Current therapeutic armamentarium for treatment of HIV-1 infection is based on the use of
highly active antiretroviral therapy that, unfortunately, does not act as a curative remedy …
highly active antiretroviral therapy that, unfortunately, does not act as a curative remedy …
Optimization of a Piperidine CD4-Mimetic Scaffold Sensitizing HIV-1 Infected Cells to Antibody-Dependent Cellular Cytotoxicity
The ability of the HIV-1 accessory proteins Nef and Vpu to decrease CD4 protects infected
cells from antibody-dependent cellular cytotoxicity (ADCC) by limiting the exposure of …
cells from antibody-dependent cellular cytotoxicity (ADCC) by limiting the exposure of …
The genesis and future prospects of small molecule HIV-1 attachment inhibitors
Gp120 is a critical viral proteins required for HIV-1 entry and infection. It facilitates HIV-1
binding to target cells, human-to-human transmission, relocation of virus from mucosa to …
binding to target cells, human-to-human transmission, relocation of virus from mucosa to …
Photocatalytic C (sp³)–C (sp²) radical-polar crossover cross-coupling of styrenyl boronic acids
J Brals - 2023 - research-repository.st-andrews.ac …
Organoboron reagents are widely used in organic chemistry due to their versatile reactivity,
ubiquity, stability, and low cost. They are commonly employed as coupling partners in cross …
ubiquity, stability, and low cost. They are commonly employed as coupling partners in cross …
Синтез піразоло [4, 3-b] піридинових систем на основі N-Bос-4-амінопіразол5-карбальдегідів
H Yakovenko - 2021 - search.proquest.com
Дисертаційна робота присвячена розробленню препаративно зручнихметодів синтезу
раніше не описаних типів функціоналізованих піразоло [4, 3-b] піридинів та …
раніше не описаних типів функціоналізованих піразоло [4, 3-b] піридинів та …
[PDF][PDF] Синтез піразоло [4, 3-b] піридинових систем на основі N-Bос-4-амінопіразол5-карбальдегідів: дисертація на здобуття наукового ступеня доктора …
Г Яковенко - 2021 - ekmair.ukma.edu.ua
НАЦІОНАЛЬНИЙ УНІВЕРСИТЕТ «КИЄВО-МОГИЛЯНСЬКА АКАДЕМІЯ» НАЦІОНАЛЬНА Page
1 НАЦІОНАЛЬНИЙ УНІВЕРСИТЕТ «КИЄВО-МОГИЛЯНСЬКА АКАДЕМІЯ» НАЦІОНАЛЬНА …
1 НАЦІОНАЛЬНИЙ УНІВЕРСИТЕТ «КИЄВО-МОГИЛЯНСЬКА АКАДЕМІЯ» НАЦІОНАЛЬНА …