Age at onset of mental disorders worldwide: large-scale meta-analysis of 192 epidemiological studies

M Solmi, J Radua, M Olivola, E Croce, L Soardo… - Molecular …, 2022 - nature.com
Promotion of good mental health, prevention, and early intervention before/at the onset of
mental disorders improve outcomes. However, the range and peak ages at onset for mental …

Altering the course of schizophrenia: progress and perspectives

MJ Millan, A Andrieux, G Bartzokis… - Nature reviews Drug …, 2016 - nature.com
Despite a lack of recent progress in the treatment of schizophrenia, our understanding of its
genetic and environmental causes has considerably improved, and their relationship to …

EPA guidance on the early detection of clinical high risk states of psychoses

F Schultze-Lutter, C Michel, SJ Schmidt… - European …, 2015 - cambridge.org
The aim of this guidance paper of the European Psychiatric Association is to provide
evidence-based recommendations on the early detection of a clinical high risk (CHR) for …

Adolescent neurodevelopment and vulnerability to psychosis

PK Patel, LD Leathem, DL Currin, KH Karlsgodt - Biological psychiatry, 2021 - Elsevier
Adolescence is characterized by significant changes in several domains, including brain
structure and function, puberty, and social and environmental factors. Some of these …

Clinical predictors of therapeutic response to antipsychotics in schizophrenia

M Carbon, CU Correll - Dialogues in clinical neuroscience, 2014 - Taylor & Francis
The search for clinical outcome predictors for schizophrenia is as old as the field of
psychiatry. However, despite a wealth of large, longitudinal studies into prognostic factors …

Age of onset and timing of treatment for mental and substance use disorders: implications for preventive intervention strategies and models of care

PD McGorry, R Purcell, S Goldstone… - Current opinion in …, 2011 - journals.lww.com
Although the onset of most mental disorders usually occurs during the first three decades of
life, effective treatment is typically not initiated until a number of years later. Although there is …

Predictors of outcome in early-onset psychosis: a systematic review

CM Díaz-Caneja, L Pina-Camacho… - npj …, 2015 - nature.com
Given the global burden of psychotic disorders, the identification of patients with early-onset
psychosis (EOP; that is, onset before the age of 18) at higher risk of adverse outcome should …

A systematic review of the long-term outcome of early onset schizophrenia

L Clemmensen, DL Vernal, HC Steinhausen - BMC psychiatry, 2012 - Springer
Background The current review analyzes the long-term outcome and prognosis of early
onset schizophrenia based on previously published studies in 1980. Methods A systematic …

Childhood-onset schizophrenia and early-onset schizophrenia spectrum disorders: an update

DI Driver, S Thomas, N Gogtay… - Child and Adolescent …, 2020 - childpsych.theclinics.com
The clinical severity, impact on development, and poor prognosis of childhoodonset
schizophrenia (COS) may represent more homogeneous forms of the disorder. 1, 2 In …

Role of social media and the I nternet in pathways to care for adolescents and young adults with psychotic disorders and non‐psychotic mood disorders

ML Birnbaum, AF Rizvi, CU Correll… - Early intervention in …, 2017 - Wiley Online Library
Aims Although psychosis often occurs during adolescence, there has been little research on
how the ubiquitously used Internet and social media could impact pathways to care. We …