Lysine acetylation is a conserved protein post-translational modification that links acetyl-
coenzyme A metabolism and cellular signalling. Recent advances in the identification and …

Owing to their crucial roles in regulating protein function, phosphorylation sites
(phosphosites) are expected to be evolutionarily conserved. However, mixed results …

The Phospho. ELM resource (http://phospho. elm. eu. org) is a relational database designed
to store in vivo and in vitro phosphorylation data extracted from the scientific literature and …

Posttranslational modifications offer a dynamic way to regulate protein activity, subcellular
localization, and stability. Here we estimate the effect of phosphorylation on protein binding …

Various post‐translational modifications (PTMs) fine‐tune the functions of almost all
eukaryotic proteins, and co‐regulation of different types of PTMs has been shown within and …

In eukaryotes, hundreds of protein kinases (PKs) specifically and precisely modify
thousands of substrates at specific amino acid residues to faithfully orchestrate numerous …

Protein (de) phosphorylation plays an important role in plants. To provide a robust
foundation for subcellular phosphorylation signaling network analysis and kinase-substrate …

Regulation of gene expression is central to many biological processes. Although
reconstruction of regulatory circuits from genomic data alone is therefore desirable, this …

Microalgae exhibit great potential for recombinant therapeutic protein production, due to
lower production costs, immunity to human pathogens, and advanced genetic toolkits …

Evolutionary profiling has been largely limited to the nucleotide level. Using consistent
proteomic methods, we quantified proteomic and phosphoproteomic layers in fibroblasts …