Protein nanoparticles: promising platforms for drug delivery applications

A Jain, SK Singh, SK Arya, SC Kundu… - … Biomaterials Science & …, 2018 - ACS Publications
The development of drug delivery systems using nanoparticles as carriers for small and
large therapeutic molecules remains a rapidly growing area of research. The advantages of …

Albumin-based nanoparticles as potential controlled release drug delivery systems

AO Elzoghby, WM Samy, NA Elgindy - Journal of controlled release, 2012 - Elsevier
Albumin, a versatile protein carrier for drug delivery, has been shown to be nontoxic, non-
immunogenic, biocompatible and biodegradable. Therefore, it is ideal material to fabricate …

Effect of size on biological properties of nanoparticles employed in gene delivery

S Prabha, G Arya, R Chandra, B Ahmed… - Artificial cells …, 2016 - Taylor & Francis
Context The size of nanoparticles plays a pivotal role in determining the gene delivery
efficiency. Objective A focus on the studies done to investigate the effect of nanoparticles …

Drug delivery of siRNA therapeutics: potentials and limits of nanosystems

D Reischl, A Zimmer - Nanomedicine: Nanotechnology, Biology and …, 2009 - Elsevier
Gene therapy is a promising tool for the treatment of human diseases that cannot be cured
by rational therapies. The major limitation for the use of small interfering RNA (siRNA), both …

A review of analytical methods for the identification and characterization of nano delivery systems in food

DMAM Luykx, RJB Peters, SM van Ruth… - Journal of agricultural …, 2008 - ACS Publications
Detection and characterization of nano delivery systems is an essential part of
understanding the benefits as well as the potential toxicity of these systems in food. This …

[HTML][HTML] Use of protamine in nanopharmaceuticals—a review

I Ruseska, K Fresacher, C Petschacher, A Zimmer - Nanomaterials, 2021 - mdpi.com
Macromolecular biomolecules are currently dethroning classical small molecule
therapeutics because of their improved targeting and delivery properties. Protamine-a small …

Nanoparticles for cellular drug delivery: mechanisms and factors influencing delivery

MD Chavanpatil, A Khdair… - Journal of nanoscience …, 2006 - ingentaconnect.com
Polymeric nanoparticles have demonstrated enormous potential as cellular drug delivery
vehicles. Nanoparticles improve drug's stability as well as its availability and retention at the …

Apolipoprotein AI coating of protamine–oligonucleotide nanoparticles increases particle uptake and transcytosis in an in vitro model of the blood–brain barrier

I Kratzer, K Wernig, U Panzenboeck, E Bernhart… - Journal of Controlled …, 2007 - Elsevier
Drug delivery to the brain is severely restricted by formation of tight junctions between
adjacent brain capillary endothelial cells (BCEC). In the present study we have evaluated …

Dual targeting nanoparticles based on hyaluronic and folic acids as a promising delivery system of the encapsulated 4-Methylumbelliferone (4-MU) against …

ML Essa, AA Elashkar, NAN Hanafy, EM Saied… - International Journal of …, 2022 - Elsevier
Lung cancer is the most common cause of cancer death worldwide. Thereby, new treatment
strategies as targeting nano-therapy present promising possibilities to control the …

Nanomedicine and drug delivery to the retina: Current status and implications for gene therapy

M Tawfik, F Chen, JL Goldberg, BA Sabel - … -schmiedeberg's Archives of …, 2022 - Springer
Blindness affects more than 60 million people worldwide. Retinal disorders, including age-
related macular degeneration (AMD), diabetic retinopathy (DR), and glaucoma, are the …