[HTML][HTML] Perinatal dietary polyunsaturated fatty acids in brain development, role in neurodevelopmental disorders

M Martinat, M Rossitto, M Di Miceli, S Layé - Nutrients, 2021 - mdpi.com
n-3 and n-6 polyunsaturated fatty acids (PUFAs) are essential fatty acids that are provided
by dietary intake. Growing evidence suggests that n-3 and n-6 PUFAs are paramount for …

Beneficial effects of omega-3 fatty acid supplementation in schizophrenia: Possible mechanisms

MC Hsu, YS Huang, WC Ouyang - Lipids in health and disease, 2020 - Springer
Background Schizophrenia is a serious long-term psychotic disorder marked by positive and
negative symptoms, severe behavioral problems and cognitive function deficits. The cause …

Nutraceuticals in psychiatric disorders: a systematic review

P Bozzatello, R Novelli, C Montemagni… - International Journal of …, 2024 - mdpi.com
Correct nutrition and diet are directly correlated with mental health, functions of the immune
system, and gut microbiota composition. Diets with a high content of some nutrients, such as …

Clinical staging for youth mental disorders: Progress in reforming diagnosis and clinical care

PD McGorry, C Mei - Annual Review of Developmental …, 2021 - annualreviews.org
Current silo-based diagnostic systems for mental disorders lack utility and fail to fulfil a
fundamental purpose of diagnosis: to guide treatment planning and predict outcomes …

Plasma polyunsaturated fatty acids and mental disorders in adolescence and early adulthood: cross-sectional and longitudinal associations in a general population …

D Mongan, C Healy, HJ Jones, S Zammit… - Translational …, 2021 - nature.com
Polyunsaturated fatty acids (PUFAs) may be pertinent to the development of mental
disorders, for example via modulation of inflammation and synaptogenesis. We wished to …

[HTML][HTML] Mental health in childhood and adolescence: The role of polyunsaturated fatty acids

P Bozzatello, C Blua, P Rocca, S Bellino - Biomedicines, 2021 - mdpi.com
There is increasing awareness of the importance of polyunsaturated fatty acids (PUFAs) for
optimal brain development and function. In recent decades, researchers have confirmed the …

Maternal separation regulates sensitivity of stress-induced depression in mice by affecting hippocampal metabolism

Y Zhang, H Wang, L Liu, X Mo, D He, X Chen… - Physiology & …, 2024 - Elsevier
Depression is a serious mental illness. Previous studies found that early life stress (ELS)
plays a vital role in the onset and progression of depression. However, relevant studies have …

Membrane lipids in ultra-high-risk patients: potential predictive biomarkers of conversion to psychosis

A Frajerman, B Chaumette, D Farabos, G Despres… - Nutrients, 2023 - mdpi.com
Alterations in membrane lipids are reported in schizophrenia. However, no conclusion can
be drawn regarding the extended and predictive value of these alterations in persons at ultra …

Peroxisome proliferator-activated receptor α as a novel therapeutic target for schizophrenia

Y Wada, M Maekawa, T Ohnishi, S Balan… - …, 2020 - thelancet.com
Background The pathophysiology of schizophrenia, a major psychiatric disorder, remains
elusive. In this study, the role of peroxisome proliferator-activated receptor (PPAR)/retinoid X …

[HTML][HTML] Peripheral lipid signatures, metabolic dysfunction, and pathophysiology in schizophrenia spectrum disorders

S Wu, KJ Panganiban, J Lee, D Li, ECC Smith… - Metabolites, 2024 - mdpi.com
Metabolic dysfunction is commonly observed in schizophrenia spectrum disorders (SSDs).
The causes of metabolic comorbidity in SSDs are complex and include intrinsic or biological …