Background: From the start of the COVID-19 pandemic, new SARS-CoV-2 variants have
emerged that potentially affect transmissibility, severity, and immune evasion in infected …

SARS-CoV-2 variants with spike (S)-protein D614G mutations now predominate globally.
We therefore compare the properties of the mutated S protein (SG614) with the original …

Antigenic characterization of emerging and re-emerging viruses is necessary for the
prevention of and response to outbreaks, evaluation of infection mechanisms …

Summary The World Health Organization declared mpox a public health emergency of
international concern in July 2022. To investigate global mpox transmission and population …

SARS-CoV-2 can mutate and evade immunity, with consequences for efficacy of emerging
vaccines and antibody therapeutics. Here, we demonstrate that the immunodominant SARS …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) hybrid immunity is more
protective than vaccination or previous infection alone. To investigate the kinetics of spike …

Humoral immunity to SARS-CoV-2 can be supplemented with polyclonal sera from
convalescent donors or an engineered monoclonal antibody (mAb) product. While …

Many SARS-CoV-2 variants have mutations at key sites targeted by antibodies. However, it
is unknown if antibodies elicited by infection with these variants target the same or different …

Quantifying transmission intensity and heterogeneity is crucial to ascertain the threat posed
by infectious diseases and inform the design of interventions. Methods that jointly estimate …

Bayesian phylogeographic inference is a powerful tool in molecular epidemiological studies,
which enables reconstruction of the origin and subsequent geographic spread of pathogens …