Proton therapy treatments are based on a proton RBE (relative biological effectiveness)
relative to high-energy photons of 1.1. The use of this generic, spatially invariant RBE within …

Significance: Extensive research during the last quarter century has revealed that reactive
oxygen species (ROS) produced in the body, primarily by the mitochondria, play a major role …

In addition to the physical advantages (Bragg peak), the use of charged particles in cancer
therapy can be associated with distinct biological effects compared to X-rays. While heavy …

All life forms have evolved under the constant force of gravity on Earth and developed ways
to counterbalance acceleration load. In space, shear forces, buoyance-driven convection …

Glioblastoma multiforme (GBM) is among the most lethal of human malignancies. Most GBM
tumors are refractory to cytotoxic therapies. Glioma stem cells (GSCs) significantly contribute …

An understanding of proton radiobiology is critical for optimization of both proton
radiotherapy and assessment of carcinogenesis risk from space radiation. Although the …

High-energy protons and carbon ions exhibit an inverse dose profile allowing for increased
energy deposition with penetration depth. Additionally, heavier ions like carbon beams have …

Despite the existence of a legislation regarding food contaminants, food safety control in
Serbia is a matter of great concern. This study investigates the radioactivity levels and heavy …

The purpose of this study was to identify the roles of non-homologous end-joining (NHEJ) or
homologous recombination (HR) pathways in repairing DNA double-strand breaks (DSBs) …

DNA damage and repair studies are at the core of the radiation biology field and represent
also the fundamental principles informing radiation therapy (RT). DNA damage levels are a …