[HTML][HTML] Mechanism of harm from left bundle branch block

OA Smiseth, JM Aalen - Trends in cardiovascular medicine, 2019 - Elsevier
The impact of left bundle branch block (LBBB) on cardiac mechanical function ranges from
minimal effect in some patients to marked reduction in left ventricular (LV) systolic function in …

Idiopathic/Iatrogenic Left Bundle Branch Block–Induced Reversible Left Ventricle Dysfunction: JACC State-of-the-Art Review

V Auffret, RP Martins, C Daubert, C Leclercq… - Journal of the American …, 2018 - jacc.org
Idiopathic or iatrogenic left bundle branch block (LBBB) is a unique model of electro-
mechanical ventricular dyssynchrony with concordant changes in electrical activation …

Impaired recovery of left ventricular function in patients with cardiomyopathy and left bundle branch block

E Sze, Z Samad, A Dunning, KB Campbell… - Journal of the American …, 2018 - jacc.org
Background: Patients with left bundle branch block (LBBB) often respond to cardiac
resynchronization therapy (CRT) with left ventricular ejection fraction (LVEF) improvement …

[HTML][HTML] Beyond conduction impairment: unveiling the profound myocardial injury in left bundle branch block

X Wang, B Ge, C Miao, C Lee, JE Romero, P Li… - Heart Rhythm, 2024 - Elsevier
Background Left bundle branch block (LBBB) represents a frequently encountered
conduction system disorder. Despite its widespread occurrence, a continual dilemma …

A strain-based staging classification of left bundle branch block-induced cardiac remodeling

S Calle, V Kamoen, M De Buyzere, J De Pooter… - Cardiovascular …, 2021 - jacc.org
Objectives This study speculated that longitudinal strain curves in left bundle branch block
(LBBB) could be shaped by the degree of LBBB-induced cardiac remodeling. Background …

Left bundle branch block-induced left ventricular remodeling and its potential for reverse remodeling

E Sze, JP Daubert - Journal of Interventional Cardiac Electrophysiology, 2018 - Springer
With the emergence of cardiac resynchronization therapy (CRT) as a powerful tool to
reverse left ventricular dysfunction in patients with left bundle branch block (LBBB), there is …

Left bundle branch area pacing with or without conduction system capture in heart failure models

S Cheng, H Li, Y Hu, H **, S Weng, P He… - Clinical …, 2024 - jacc.org
Background Left bundle branch area pacing includes left bundle branch pacing (LBBP) and
left ventricular septal pacing (LVSP), which is effective in patients with dyssynchronous heart …

His‐bundle pacing: a novel treatment for left bundle branch block‐mediated cardiomyopathy

R Singh, S Devabhaktuni, F Ezzeddine… - Journal of …, 2020 - Wiley Online Library
Background Chronic left bundle branch block (LBBB) can lead to LBBB‐mediated
cardiomyopathy from left ventricular dysynchrony. His‐bundle pacing (HBP) results in direct …

Impact of QRS duration on left ventricular remodelling and survival in patients with heart failure

S Straw, M McGinlay, J Gierula, JE Lowry… - Journal of …, 2021 - journals.lww.com
Aims In patients with chronic heart failure, QRS duration is a consistent predictor of poor
outcomes. It has been suggested that for indicated patients, cardiac resynchronization …

Risk and predictors of dyssynchrony cardiomyopathy in left bundle branch block with preserved left ventricular ejection fraction

S Sharma, HV Barot, AD Schwartzman… - Clinical …, 2020 - Wiley Online Library
Background Left bundle branch block (LBBB) and left ventricular (LV) dyssynchrony likely
contribute to progressive systolic dysfunction. The evaluation of newly recognized LBBB …