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The synapse in traumatic brain injury
Traumatic brain injury (TBI) is a leading cause of death and disability worldwide and is a risk
factor for dementia later in life. Research into the pathophysiology of TBI has focused on the …
factor for dementia later in life. Research into the pathophysiology of TBI has focused on the …
Translational research in traumatic brain injury
D Laskowitz, G Grant - 2016 - books.google.com
Traumatic brain injury (TBI) remains a significant source of death and permanent disability,
contributing to nearly one-third of all injury related deaths in the United States and exacting …
contributing to nearly one-third of all injury related deaths in the United States and exacting …
Repeated mild traumatic brain injury: potential mechanisms of damage
Mild traumatic brain injury (mTBI) represents a significant public healthcare concern,
accounting for the majority of all head injuries. While symptoms are generally transient …
accounting for the majority of all head injuries. While symptoms are generally transient …
Peroxisome proliferator-activated receptor γ (PPARγ): A master gatekeeper in CNS injury and repair
Peroxisome proliferator-activated receptor γ (PPARγ) is a widely expressed ligand-
modulated transcription factor that governs the expression of genes involved in …
modulated transcription factor that governs the expression of genes involved in …
White matter involvement after TBI: Clues to axon and myelin repair capacity
RC Armstrong, AJ Mierzwa, CM Marion… - Experimental …, 2016 - Elsevier
Impact-acceleration forces to the head cause traumatic brain injury (TBI) with damage in
white matter tracts comprised of long axons traversing the brain. White matter injury after TBI …
white matter tracts comprised of long axons traversing the brain. White matter injury after TBI …
Components of myelin damage and repair in the progression of white matter pathology after mild traumatic brain injury
AJ Mierzwa, CM Marion, GM Sullivan… - … of Neuropathology & …, 2015 - academic.oup.com
White matter tracts are highly vulnerable to damage from impact-acceleration forces of
traumatic brain injury (TBI). Mild TBI is characterized by a low density of traumatic axonal …
traumatic brain injury (TBI). Mild TBI is characterized by a low density of traumatic axonal …
Astrocyte‐mediated mechanisms contribute to traumatic brain injury pathology
Astrocytes respond to traumatic brain injury (TBI) with changes to their molecular make‐up
and cell biology, which results in changes in astrocyte function. These changes can be …
and cell biology, which results in changes in astrocyte function. These changes can be …
[HTML][HTML] White matter damage and degeneration in traumatic brain injury
Traumatic brain injury (TBI) is a complex condition that can resolve over time but all too often
leads to persistent symptoms, and the risk of poor patient outcomes increases with aging …
leads to persistent symptoms, and the risk of poor patient outcomes increases with aging …
Myelin and oligodendrocyte lineage cells in white matter pathology and plasticity after traumatic brain injury
Impact to the head or rapid head acceleration–deceleration can cause traumatic brain injury
(TBI) with a characteristic pathology of traumatic axonal injury (TAI) and secondary damage …
(TBI) with a characteristic pathology of traumatic axonal injury (TAI) and secondary damage …
Experimental traumatic brain injury identifies distinct early and late phase axonal conduction deficits of white matter pathophysiology, and reveals intervening recovery
CM Marion, KL Radomski, NP Cramer… - Journal of …, 2018 - jneurosci.org
Traumatic brain injury (TBI) patients often exhibit slowed information processing speed that
can underlie diverse symptoms. Processing speed depends on neural circuit function at …
can underlie diverse symptoms. Processing speed depends on neural circuit function at …