Chronic inflammation may increase the risk to develop cancer, for instance esophagitis or
gastritis may lead to development of esophageal or gastric cancer, respectively. The key …

Gastric cancer (GC) is the fifth most common cancer and the fourth most common cause of
cancer-related death worldwide. The intestinal type of GC progresses from acute to chronic …

Background/Purpose Helicobacter pylori-induced gastric mucosal inflammation is mediated
by proinflammatory and anti-inflammatory cytokines. Polymorphisms in genes that code …

The innate immune response is a critical hallmark of Helicobacter pylori infection. Epithelial
and myeloid cells produce effectors, including the chemokine CXCL8, reactive oxygen …

Background Potential functional allele A/T single nucleotide polymorphism (SNP) of
Interleukin 8 (IL-8) promoter-251has been implicated in gastric cancer risk. Methods We …

Abstract The− 251T/A (rs4073), a single nucleotide polymorphism, has been identified in the
promoter region of the interleukin-8 (IL-8) gene. It's presence could influence the production …

Polymorphisms in gene encoding programmed death-1 (PD-1) were suggested to be
associated with the risk of multiple cancers. To the best of our knowledge, no investigation …

ABSTRACT Background and Objective: Interleukin‐8 (IL‐8) is a central chemokine in acute
respiratory distress syndrome (ARDS), and the IL‐8 gene contains a functional single …

Backgrounds The associations between the polymorphisms of interleukin-8 (IL-8) gene and
gastric carcinogenesis have been extensively investigated in recent years. However, the …

Abstract Interleukin-6 (IL-6) is a multifunctional cytokine involved in different physiologic and
pathophysiologic processes and plays important roles in the etiology of cancer. The− 174G> …