Arginine methylation is a common post-translational modification functioning as an
epigenetic regulator of transcription and playing key roles in pre-mRNA splicing, DNA …

In the embryonic and adult brain, neural stem cells proliferate and give rise to neurons and
glia through highly regulated processes. Epigenetic mechanisms—including DNA and …

Evolutionary expansion of the human neocortex reflects increased amplification of basal
progenitors in the subventricular zone, producing more neurons during fetal corticogenesis …

The size and extent of folding of the mammalian cerebral cortex are important factors that
influence a species' cognitive abilities and sensorimotor skills. Studies in various animal …

During vertebrate development, a wide variety of cell types and tissues emerge from a single
fertilized oocyte. One of these tissues, the central nervous system, contains many types of …

The T-box family of transcription factors exhibits widespread involvement throughout
development in all metazoans. T-box proteins are characterized by a DNA-binding motif …

Evolutionary expansion and complexification of the primate cerebral cortex are largely
linked to the emergence of the outer subventricular zone (OSVZ), a uniquely structured …

MiR-17-92 cluster enriched exosomes derived from multipotent mesenchymal stromal cells
(MSCs) increase functional recovery after stroke. Here, we investigate the mechanisms …

Background The endoplasmic reticulum (ER) is responsible for the control of correct protein
folding and protein function which is crucial for cell survival. However, under pathological …

Transient transfection of chemically synthesized microRNA (miRNA) mimics is being used
extensively to study the functions and mechanisms of endogenous miRNAs. However, it …