Clostridioides difficile is the most common cause of nosocomial antibiotic-associated
diarrhea, and is responsible for a spectrum of diseases characterized by high levels of …

Clostridioides difficile is a Gram-positive, spore-forming, anaerobic bacterium. The clinical
features of C. difficile infections (CDIs) can vary, ranging from the asymptomatic carriage and …

Deinococcus radiodurans is an atypical diderm bacterium with a remarkable ability to
tolerate various environmental stresses, due in part to its complex cell envelope …

Surface layers (S-layers) are proteinaceous, two-dimensional paracrystalline arrays that
constitute a major component of the cell envelope in many prokaryotic species. In this study …

Surface layers (S-layers) are resilient two-dimensional protein lattices that encapsulate
many bacteria and most archaea. In archaea, S-layers usually form the only structural …

The symptoms of Clostridioides difficile infection (CDI) are largely attributed to two C. difficile
toxins, TcdA and TcdB. Significant efforts have been devoted to develo** vaccines …

Controllable protein nanoarchitectonics refers to the process of manipulating and controlling
the assembly of proteins at the nanoscale to achieve domain‐limited and accurate spatial …

ABSTRACT Clostridioides difficile (C. difficile), a gram-positive anaerobic and spore-forming
bacterium, is the leading cause of nosocomial antibiotic-associated diarrhea in adults which …

Endolysin is a phage-encoded cell-wall hydrolase which degrades the peptidoglycan layer
of the bacterial cell wall. The enzyme is often expressed at the late stage of the phage lytic …

Therapeutic bacteriophages (phages) are being considered as alternatives in the fight
against Clostridioides difficile infections. To be efficient, phages should have a wide host …