Spreading depression (SD) is a transient wave of near-complete neuronal and glial
depolarization associated with massive transmembrane ionic and water shifts. It is …

The accurate segmentation of brain stroke lesions in medical images are critical for early
diagnosis, treatment planning, and monitoring of stroke patients. In recent years, deep …

The no-reflow phenomenon refers to the observation that when an organ is made ischemic
by occlusion of a large artery supplying it, restoration of patency in that artery does not …

Water diffusion magnetic resonance imaging (dMRI) allows tissue structure to be probed
and imaged on a microscopic scale, providing unique clues to the fine architecture of neural …

Diffusion MRI (or dMRI) came into existence in the mid-1980s. During the last 25years,
diffusion MRI has been extraordinarily successful (with more than 300,000 entries on …

Cerebral white matter (WM) undergoes various degenerative changes with normal aging,
including decreases in myelin density and alterations in myelin structure. We acquired …

Background and Purpose—Numerous imaging techniques have been developed and
applied to evaluate brain hemodynamics. Among these are positron emission tomography …

Relative cerebral blood flow (CBF) and tissue mean transit time (MTT) estimates from bolus‐
tracking MR perfusion‐weighted imaging (PWI) have been shown to be sensitive to delay …

Worldwide, stroke is a leading cause of death and disability. Recombinant tissue
plasminogen activator (rtPA) was approved a decade ago for the treatment of acute ischemic …

Stroke is a leading cause of death and disability worldwide. Imaging plays a critical role in
evaluating patients suspected of acute stroke and transient ischemic attack, especially …