Biomonitoring and precision health in deep space supported by artificial intelligence

RT Scott, LM Sanders, EL Antonsen… - Nature Machine …, 2023 - nature.com
Human exploration of deep space will involve missions of substantial distance and duration.
To effectively mitigate health hazards, paradigm shifts in astronaut health systems are …

Astronaut omics and the impact of space on the human body at scale

LA Rutter, H Cope, MJ MacKay, R Herranz… - Nature …, 2024 - nature.com
Future multi-year crewed planetary missions will motivate advances in aerospace nutrition
and telehealth. On Earth, the Human Cell Atlas project aims to spatially map all cell types in …

Single-cell multi-ome and immune profiles of the Inspiration4 crew reveal conserved, cell-type, and sex-specific responses to spaceflight

JK Kim, BT Tierney, EG Overbey, E Dantas… - Nature …, 2024 - nature.com
Spaceflight induces an immune response in astronauts. To better characterize this effect, we
generated single-cell, multi-ome, cell-free RNA (cfRNA), biochemical, and hematology data …

The Space Omics and Medical Atlas (SOMA) and international astronaut biobank

EG Overbey, JK Kim, BT Tierney, J Park, N Houerbi… - Nature, 2024 - nature.com
Spaceflight induces molecular, cellular and physiological shifts in astronauts and poses
myriad biomedical challenges to the human body, which are becoming increasingly relevant …

Molecular and physiological changes in the SpaceX Inspiration4 civilian crew

CW Jones, EG Overbey, J Lacombe, AJ Ecker… - Nature, 2024 - nature.com
Human spaceflight has historically been managed by government agencies, such as in the
NASA Twins Study, but new commercial spaceflight opportunities have opened spaceflight …

The 2022 Nucleic Acids Research database issue and the online molecular biology database collection

DJ Rigden, XM Fernández - Nucleic acids research, 2022 - academic.oup.com
Abstract The 2022 Nucleic Acids Research Database Issue contains 185 papers, including
87 papers reporting on new databases and 85 updates from resources previously published …

From open data to open science

R Ramachandran, K Bugbee… - Earth and Space …, 2021 - Wiley Online Library
The open science movement continues to gain momentum, attention, and discussion.
However, there are a number of different interpretations, viewpoints, and perspectives as to …

Secretome profiling reveals acute changes in oxidative stress, brain homeostasis, and coagulation following short-duration spaceflight

N Houerbi, JK Kim, EG Overbey, R Batra… - Nature …, 2024 - nature.com
As spaceflight becomes more common with commercial crews, blood-based measures of
crew health can guide both astronaut biomedicine and countermeasures. By profiling …

Biological research and self-driving labs in deep space supported by artificial intelligence

LM Sanders, RT Scott, JH Yang, AA Qutub… - Nature Machine …, 2023 - nature.com
Abstract Space biology research aims to understand fundamental spaceflight effects on
organisms, develop foundational knowledge to support deep space exploration and …

[HTML][HTML] Satellite-enabled enviromics to enhance crop improvement

RT Resende, L Hickey, CH Amaral, LL Peixoto… - Molecular Plant, 2024 - cell.com
Enviromics refers to the characterization of micro-and macroenvironments based on large-
scale environmental datasets. By providing genotypic recommendations with predictive …