Revisiting the significance of natural protease inhibitors: A comprehensive review

DC Paul, M Bhattacharjee - International Journal of Biological …, 2024 - Elsevier
Protease inhibitors (PIs) function as a natural adversary to proteolytic enzymes. They can
diminish or inhibit the catalytic properties of proteases, which are crucial for various tasks in …

Pleiotropic effects of recombinant protease inhibitors in plants

P Mangena - Frontiers in Plant Science, 2022 - frontiersin.org
Recombinant gene encoded protease inhibitors have been identified as some of the most
effective antidigestive molecules to guard against proteolysis of essential proteins and plant …

Trypsin Inhibitor from Soybean Whey Wastewater: Isolation, Purification and Stability

Y Zhang, Y Zhang, Z Ying, W Li, H Li, X Liu - Applied Sciences, 2022 - mdpi.com
Soybean trypsin inhibitor (STI) was obtained from simulated soybean whey wastewater
through a sustainable method consisting of isoelectric precipitation, ammonium sulfate …

Development of a rapid process for purification of Bowman-Birk and Kunitz inhibitors from legume seeds, and evaluation of their biophysical, insecticidal, and …

M Gujjarlapudi, B Kotarya, SS Mohanraj… - International Journal of …, 2023 - Elsevier
Abstract Bowman-Birk inhibitor (BBI~ 10 kDa) and Kunitz inhibitor (KI~ 20 kDa) are serine
protease/proteinase inhibitor (s)[PI (s)] ubiquitously found in several Leguminous plant …

Kinetic and mechanistic study of ultrasonic inactivation of Kunitz (KTI) and Bowman-Birk (BBI) inhibitors in relation to process-relevant parameters

Y Wu, W Li, E Colombo, GJO Martin, M Ashokkumar - Food Chemistry, 2023 - Elsevier
In this study, quantitative monitoring of low-frequency (20 kHz) and high-frequency (355
kHz) ultrasound-induced inactivation of Kunitz (KTI) and Bowman-Birk inhibitor (BBI) using …

In vivo developmental studies of Helicoverpa armigera and in silico molecular interactions with trypsin reveal the bio-insecticidal potential of trypsin inhibitor (SSTI) …

AP Herwade, SS Barale, KD Sonawane… - International Journal of …, 2022 - Elsevier
We report the impact of gut protease inhibition on the development of Helicoverpa armigera
by trypsin inhibitor and the use of molecular modeling to understand the mechanism of …

Assessment of soy genotype and processing method on trypsin inhibitors, urease and lectins content of tofu

SP Stanojević, AŽ Kostić, DD Milinčić… - Natural Product …, 2024 - Taylor & Francis
Tofu has a high nutritional value, but it may also contain components that may have an
antinutritional effect, such as trypsin inhibitors (TI), lectins and ureases. The aim of this study …

[PDF][PDF] Evaluation of the Anti-Inflammatory, Antioxidant, and Protease Inhibitory Activity of the Crude Methanol Extract of Portulaca oleracea.

AA Sohemat, OM Atrooz, HS Farah - Tropical Journal of Natural …, 2023 - researchgate.net
Protease inhibitors have considerable applications in biomedicine, biotechnology, and
therapy. The aim of the study was to evaluate the methanol crude extracts of aerial portions …

Comparative Binding Affinity Analysis of Soybean Meal Bowman-Birk and Kunitz Trypsin Inhibitors in Interactions with Animal Serine Proteases

AO Okedigba, ML Rosso, D Yu, C Shang… - ACS Food Science & …, 2023 - ACS Publications
Raw soybeans are not suitable for consumption due to their high levels of anti-nutritional
factors, such as trypsin inhibitors (TIs). The two main TIs in soybean, the Kunitz trypsin …

Antimicrobial and antibiofilm activities of Inga cylindrica trypsin inhibitor

APR Pereira, AC Jacobowski, JCO Sardi… - Brazilian Journal of …, 2024 - SciELO Brasil
Inga cylindrica, a tropical fruit tree of the Fabaceae family (subfamily Mimosoideae), is native
to South America. The seeds from this family are an essential source of trypsin inhibitors …