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Classic serotonergic psychedelics for mood and depressive symptoms: a meta-analysis of mood disorder patients and healthy participants
Rationale Major depressive disorder is one of the leading global causes of disability, for
which the classic serotonergic psychedelics have recently reemerged as a potential …
which the classic serotonergic psychedelics have recently reemerged as a potential …
Novel drug developmental strategies for treatment‐resistant depression
Major depressive disorder is a leading cause of disability worldwide. Because conventional
therapies are ineffective in many patients, novel strategies are needed to overcome …
therapies are ineffective in many patients, novel strategies are needed to overcome …
Acute and sustained reductions in loss of meaning and suicidal ideation following psilocybin-assisted psychotherapy for psychiatric and existential distress in life …
People with advanced cancer are at heightened risk of desire for hastened death (DHD),
suicidal ideation (SI), and completed suicide. Loss of Meaning (LoM), a component of …
suicidal ideation (SI), and completed suicide. Loss of Meaning (LoM), a component of …
Post-psychedelic reductions in experiential avoidance are associated with decreases in depression severity and suicidal ideation
Psychedelic therapy shows promise as a novel intervention for a wide range of mental
health concerns but its therapeutic action is incompletely understood. In line with …
health concerns but its therapeutic action is incompletely understood. In line with …
Does psychedelic therapy have a transdiagnostic action and prophylactic potential?
Addressing global mental health is a major 21st-century challenge. Current treatments have
recognized limitations; in this context, new ones that are prophylactic and effective across …
recognized limitations; in this context, new ones that are prophylactic and effective across …
The Canadian Network for Mood and Anxiety Treatments (CANMAT) task force report: serotonergic psychedelic treatments for major depressive disorder
Objective Serotonergic psychedelics are re-emerging as potential novel treatments for
several psychiatric disorders including major depressive disorder. The Canadian Network …
several psychiatric disorders including major depressive disorder. The Canadian Network …
MDMA/ecstasy use and psilocybin use are associated with lowered odds of psychological distress and suicidal thoughts in a sample of US adults
Background: Suicide is one of the leading causes of death worldwide and rates within the
United States have risen over the past two decades. Hence, there is a critical need for novel …
United States have risen over the past two decades. Hence, there is a critical need for novel …
Rapid and sustained decreases in suicidality following a single dose of ayahuasca among individuals with recurrent major depressive disorder: results from an open …
Rationale Suicidality is a major public health concern with limited treatment options.
Accordingly, there is a need for innovative interventions for suicidality. Preliminary evidence …
Accordingly, there is a need for innovative interventions for suicidality. Preliminary evidence …
Control conditions in randomized trials of psychedelics: an ACTTION systematic review
Results: In total, 126 articles were included, encompassing 86 unique studies. Of studies
with a drug control condition (80), 49 (61.2%) used an inert placebo control, 16 (20.0%) …
with a drug control condition (80), 49 (61.2%) used an inert placebo control, 16 (20.0%) …
Psychedelics: alternative and potential therapeutic options for treating mood and anxiety disorders
H Lowe, N Toyang, B Steele, J Grant, A Ali, L Gordon… - Molecules, 2022 - mdpi.com
The word “psychedelic”(psyche (ie, the mind or soul) and delos (ie, to show)) has Greek
origin and was first coined by psychiatrist Humphry Osmond in 1956, who had been …
origin and was first coined by psychiatrist Humphry Osmond in 1956, who had been …