Delayed cerebral ischemia after subarachnoid hemorrhage

A Ikram, MA Javaid, S Ortega-Gutierrez, M Selim… - Journal of Stroke and …, 2021 - Elsevier
Delayed cerebral ischemia (DCI) is the most feared complication of aneurysmal
subarachnoid hemorrhage (aSAH). It increases the mortality and morbidity associated with …

Chronic stress and endothelial dysfunction: mechanisms, experimental challenges, and the way ahead

LD Sher, H Geddie, L Olivier… - American Journal …, 2020 - journals.physiology.org
Although chronic stress is an important risk factor for cardiovascular diseases (CVD) onset,
the underlying mechanisms driving such pathophysiological complications remain relatively …

Dysregulation of stress systems and nitric oxide signaling underlies neuronal dysfunction in Alzheimer's disease

JG Spiers, HJC Chen, JM Bourgognon… - Free Radical Biology and …, 2019 - Elsevier
Stress is a multimodal response involving the coordination of numerous body systems in
order to maximize the chance of survival. However, long term activation of the stress …

Melatonin reverses the loss of the anticontractile effect of perivascular adipose tissue in obese rats

NA Gonzaga, WMC Awata, SP Ficher… - Journal of Pineal …, 2021 - Wiley Online Library
Perivascular adipose tissue (PVAT) undergoes functional changes in obesity. Increased
oxidative stress is a central mechanism whereby obesity induces loss of the anticontractile …

Effects of a Macroporous Resin Extract of Dendrobium officinale Leaves in Rats with Hyperuricemia Induced by Anthropomorphic Unhealthy Lifestyle

LZ Li, XM Wang, XJ Feng, K Liu, B Li… - Evidence‐Based …, 2023 - Wiley Online Library
Aim. Hyperuricemia (HUA) has received increased attention in the last few decades due to
its global prevalence. Our previous study found that administration of a macroporous resin …

Ethanol consumption favors pro-contractile phenotype of perivascular adipose tissue: A role for interleukin-6

JA Simplicio, TMH Dourado, WMC Awata, GT do Vale… - Life Sciences, 2023 - Elsevier
Perivascular adipose tissue (PVAT) exerts anticontractile effect, but under non-physiological
conditions it may contribute to vascular dysfunction by releasing pro-inflammatory cytokines …

Mineralocorticoid receptor antagonism partially prevents dysfunction of T cell maturation in rats chronically treated with ethanol

TMH Dourado, DC Nascimento, MH Rosa… - Naunyn-Schmiedeberg's …, 2024 - Springer
Ethanol consumption induces thymic atrophy and affects T cell maturation in the thymus.
However, the mechanisms underlying such effects still need to be fully understood. We …

Reactive oxygen species derived from NAD (P) H oxidase play a role on ethanol-induced hypertension and endothelial dysfunction in rat resistance arteries

JA Simplicio, GT do Vale, NA Gonzaga… - Journal of physiology …, 2017 - Springer
Chronic ethanol consumption is a risk factor for cardiovascular diseases. We studied
whether NAD (P) H oxidase-derived reactive oxygen species (ROS) play a role in ethanol …

NADPH oxidase plays a role on ethanol-induced hypertension and reactive oxygen species generation in the vasculature

KC Marchi, CS Ceron, JJ Muniz… - Alcohol and …, 2016 - academic.oup.com
Aims Investigate the role of NADPH oxidase on ethanol-induced hypertension and vascular
oxidative stress. Methods Male Wistar rats were treated with ethanol (20% v/v). Results …

Posttraumatic stress disorder disturbs coronary tone and its regulatory mechanisms

SS Lazuko, OP Kuzhel, LE Belyaeva… - Cellular and molecular …, 2018 - Springer
Posttraumatic stress disorder (PTSD) is associated with myocardial injury, but changes in
coronary regulatory mechanisms in PTSD have not been investigated. This study evaluated …