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Beneath the radar: immune-evasive cell sources for stroke therapy
Stem cell therapy is an emerging treatment paradigm for stroke patients with remaining
neurological deficits. While allogeneic cell transplants overcome the manufacturing …
neurological deficits. While allogeneic cell transplants overcome the manufacturing …
Deep learning-based behavioral profiling of rodent stroke recovery
Background Stroke research heavily relies on rodent behavior when assessing underlying
disease mechanisms and treatment efficacy. Although functional motor recovery is …
disease mechanisms and treatment efficacy. Although functional motor recovery is …
[HTML][HTML] A toolkit for stroke infarct volume estimation in rodents
Stroke volume is a key determinant of infarct severity and an important metric for evaluating
treatments. However, accurate estimation of stroke volume can be challenging, due to the …
treatments. However, accurate estimation of stroke volume can be challenging, due to the …
Xeno-free induced pluripotent stem cell-derived neural progenitor cells for in vivo applications
Background Currently, there is no regenerative therapy for patients with neurological and
neurodegenerative disorders. Cell-therapies have emerged as a potential treatment for …
neurodegenerative disorders. Cell-therapies have emerged as a potential treatment for …
Human iPSC-derived cell grafts promote functional recovery by molecular interaction with stroke-injured brain
Stroke is a leading cause of disability and death due to the brain's limited ability to
regenerate damaged neural circuits. To date, stroke patients have only few therapeutic …
regenerate damaged neural circuits. To date, stroke patients have only few therapeutic …
A molecular brain atlas reveals cellular shifts during the repair phase of stroke
Ischemic stroke triggers a cascade of pathological events that affect multiple cell types and
often lead to incomplete functional recovery. Despite advances in single-cell technologies …
often lead to incomplete functional recovery. Despite advances in single-cell technologies …
Effects of Muse Cell on a Mouse Model With Acute Encephalopathy
T Kawaguchi, T Mori, K Adachi, J Fujii… - Brain and …, 2025 - Wiley Online Library
Introduction Acute encephalopathy (AE) in childhood due to a viral infection causes
convulsions and altered consciousness, leading to severe sequelae and death. Among the …
convulsions and altered consciousness, leading to severe sequelae and death. Among the …
Visualization and estimation of stroke infarct volumes in rodents
Stroke volume is a key determinant of infarct severity and an important metric treatments
evaluation. However, accurate estimation of stroke volume can be challenging, due to the …
evaluation. However, accurate estimation of stroke volume can be challenging, due to the …
Delayed transplantation of neural stem cells improves initial graft survival following stroke
Neural stem cell therapies hold great promise for improving stroke recovery, but the hostile
stroke microenvironment can hinder the initial graft survival. It has long been well …
stroke microenvironment can hinder the initial graft survival. It has long been well …
[HTML][HTML] Dataset on stroke infarct volume in rodents: A comparison of MRI and histological methods
This dataset offers images of mouse brains impacted by photothrombotic stroke in the
sensorimotor cortex published by Weber et al. NeuroImage (2024). Data is gathered using …
sensorimotor cortex published by Weber et al. NeuroImage (2024). Data is gathered using …