Beneath the radar: immune-evasive cell sources for stroke therapy

BA Buil, NH Rentsch, RZ Weber, C Rickenbach… - Trends in Molecular …, 2024 - cell.com
Stem cell therapy is an emerging treatment paradigm for stroke patients with remaining
neurological deficits. While allogeneic cell transplants overcome the manufacturing …

Deep learning-based behavioral profiling of rodent stroke recovery

RZ Weber, G Mulders, J Kaiser, C Tackenberg, R Rust - BMC biology, 2022 - Springer
Background Stroke research heavily relies on rodent behavior when assessing underlying
disease mechanisms and treatment efficacy. Although functional motor recovery is …

[HTML][HTML] A toolkit for stroke infarct volume estimation in rodents

RZ Weber, D Bernardoni, NH Rentsch, BA Buil… - Neuroimage, 2024 - Elsevier
Stroke volume is a key determinant of infarct severity and an important metric for evaluating
treatments. However, accurate estimation of stroke volume can be challenging, due to the …

Xeno-free induced pluripotent stem cell-derived neural progenitor cells for in vivo applications

R Rust, RZ Weber, M Generali, D Kehl… - Journal of Translational …, 2022 - Springer
Background Currently, there is no regenerative therapy for patients with neurological and
neurodegenerative disorders. Cell-therapies have emerged as a potential treatment for …

Human iPSC-derived cell grafts promote functional recovery by molecular interaction with stroke-injured brain

RZ Weber, B Achón Buil, NH Rentsch, P Perron… - bioRxiv, 2024 - biorxiv.org
Stroke is a leading cause of disability and death due to the brain's limited ability to
regenerate damaged neural circuits. To date, stroke patients have only few therapeutic …

A molecular brain atlas reveals cellular shifts during the repair phase of stroke

RZ Weber, BA Buil, NH Rentsch, A Bosworth… - Biorxiv, 2024 - pmc.ncbi.nlm.nih.gov
Ischemic stroke triggers a cascade of pathological events that affect multiple cell types and
often lead to incomplete functional recovery. Despite advances in single-cell technologies …

Effects of Muse Cell on a Mouse Model With Acute Encephalopathy

T Kawaguchi, T Mori, K Adachi, J Fujii… - Brain and …, 2025 - Wiley Online Library
Introduction Acute encephalopathy (AE) in childhood due to a viral infection causes
convulsions and altered consciousness, leading to severe sequelae and death. Among the …

Visualization and estimation of stroke infarct volumes in rodents

RZ Weber, D Bernardoni, NH Rentsch, B Achón Buil… - bioRxiv, 2023 - biorxiv.org
Stroke volume is a key determinant of infarct severity and an important metric treatments
evaluation. However, accurate estimation of stroke volume can be challenging, due to the …

Delayed transplantation of neural stem cells improves initial graft survival following stroke

RZ Weber, NH Rentsch, BA Buil, LR Nih, C Tackenberg… - bioRxiv, 2025 - biorxiv.org
Neural stem cell therapies hold great promise for improving stroke recovery, but the hostile
stroke microenvironment can hinder the initial graft survival. It has long been well …

[HTML][HTML] Dataset on stroke infarct volume in rodents: A comparison of MRI and histological methods

RZ Weber, D Bernardoni, NH Rentsch, BA Buil… - Data in Brief, 2024 - Elsevier
This dataset offers images of mouse brains impacted by photothrombotic stroke in the
sensorimotor cortex published by Weber et al. NeuroImage (2024). Data is gathered using …