Immunity of the greater wax moth Galleria mellonella

I Wojda - Insect science, 2017 - Wiley Online Library
Investigation of insect immune mechanisms provides important information concerning
innate immunity, which in many aspects is conserved in animals. This is one of the reasons …

Galleria mellonella as a consolidated in vivo model hosts: New developments in antibacterial strategies and novel drug testing

MA Cutuli, G Petronio Petronio, F Vergalito, I Magnifico… - Virulence, 2019 - Taylor & Francis
ABSTRACT A greater ethical conscience, new global rules and a modified perception of
ethical consciousness entail a more rigorous control on utilizations of vertebrates for in vivo …

Yeast‐insect associations: It takes guts

I Stefanini - Yeast, 2018 - Wiley Online Library
Insects interact with microorganisms in several situations, ranging from the accidental
interaction to locate attractive food or the acquisition of essential nutrients missing in the …

Aspergillus and aspergilloses in wild and domestic animals: a global health concern with parallels to human disease

S Seyedmousavi, J Guillot, P Arné… - Medical …, 2015 - academic.oup.com
The importance of aspergillosis in humans and various animal species has increased over
the last decades. Aspergillus species are found worldwide in humans and in almost all …

Galleria mellonella larvae as an infection model for group A streptococcus

JMS Loh, N Adenwalla, S Wiles, T Proft - Virulence, 2013 - Taylor & Francis
Group A streptococcus is a strict human pathogen that can cause a wide range of diseases,
such as tonsillitis, impetigo, necrotizing fasciitis, toxic shock, and acute rheumatic fever …

Galleria mellonella as a Model for the Study of Fungal Pathogens: Advantages and Disadvantages

A Giammarino, N Bellucci, L Angiolella - Pathogens, 2024 - mdpi.com
The study of pathogenicity and virulence of fungal strains, in vivo in the preclinical phase, is
carried out through the use of animal models belonging to various classes of mammals …

What Can We Learn About Human Disease from the Nematode C. elegans?

J Apfeld, S Alper - Disease Gene Identification: Methods and Protocols, 2018 - Springer
Numerous approaches have been taken in the hunt for human disease genes. The
identification of such genes not only provides a great deal of information about the …

Methodologies for in vitro and in vivo evaluation of efficacy of antifungal and antibiofilm agents and surface coatings against fungal biofilms

P Van Dijck, J Sjollema, BPA Cammue… - Microbial …, 2018 - pmc.ncbi.nlm.nih.gov
Unlike superficial fungal infections of the skin and nails, which are the most common fungal
diseases in humans, invasive fungal infections carry high morbidity and mortality …

Inhibiting fungal multidrug resistance by disrupting an activator–mediator interaction

JL Nishikawa, A Boeszoermenyi, LA Vale-Silva… - Nature, 2016 - nature.com
Eukaryotic transcription activators stimulate the expression of specific sets of target genes
through recruitment of co-activators such as the RNA polymerase II-interacting Mediator …

The Use of Galleria mellonella Larvae to Identify Novel Antimicrobial Agents against Fungal Species of Medical Interest

K Kavanagh, G Sheehan - Journal of Fungi, 2018 - mdpi.com
The immune system of insects and the innate immune response of mammals share many
similarities and, as a result, insects may be used to assess the virulence of fungal pathogens …