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An overview of nanostructured lipid carriers and its application in drug delivery through different routes
S Khan, A Sharma, V Jain - Advanced pharmaceutical bulletin, 2022 - pmc.ncbi.nlm.nih.gov
Nanostructured Lipid Carriers (NLC) are nano-sized colloidal drug delivery system that
contains a lipid mixture consisting of both solid and liquid lipids in their core. This Lipid …
contains a lipid mixture consisting of both solid and liquid lipids in their core. This Lipid …
[HTML][HTML] Nanostructured lipid carriers and their potential applications for versatile drug delivery via oral administration
Enteral administration is the most convenient route despite the gastrointestinal physiological
barriers. Nanostructured lipid carriers (NLCs) have emerged as a promising strategy for …
barriers. Nanostructured lipid carriers (NLCs) have emerged as a promising strategy for …
[HTML][HTML] Recent progress of lipid nanoparticles-based lipophilic drug delivery: focus on surface modifications
Numerous drugs have emerged to treat various diseases, such as COVID-19, cancer, and
protect human health. Approximately 40% of them are lipophilic and are used for treating …
protect human health. Approximately 40% of them are lipophilic and are used for treating …
Nanostructured lipid carriers: a promising drug carrier for targeting brain tumours
Background In recent years, the field of nanotechnology and nanomedicine has transformed
the pharmaceutical industry with the development of novel drug delivery systems that …
the pharmaceutical industry with the development of novel drug delivery systems that …
Chitosan surface-modified PLGA nanoparticles loaded with cranberry powder extract as a potential oral delivery platform for targeting colon cancer cells
Nutraceutical cranberry powder extract (CBPE) has distinct polyphenols inhibiting colon
cancer growth and proliferation. However, its oral therapeutic efficacy is hindered because …
cancer growth and proliferation. However, its oral therapeutic efficacy is hindered because …
Nanostructured lipid carriers for improved delivery of therapeutics via the oral route
Drug delivery via the oral route has always been challenging for poorly soluble drugs. Acid‐
induced hydrolysis, enzymatic degradation, and poor mucosal absorbency remain the …
induced hydrolysis, enzymatic degradation, and poor mucosal absorbency remain the …
TPGS surface modified bilosomes as boosting cytotoxic oral delivery systems of curcumin against doxorubicin resistant MCF-7 breast cancer cells
The goal of this work was to design nude bilosomes (Bil) and D-alpha-tocopheryl
polyethylene glycol succinate (TPGS) surface coated bilosomes as an oral delivery platform …
polyethylene glycol succinate (TPGS) surface coated bilosomes as an oral delivery platform …
Nose to brain delivery of mirtazapine via lipid nanocapsules: Preparation, statistical optimization, radiolabeling, in vivo biodistribution and pharmacokinetic study
Mirtazapine (MZPc) is an antidepressant drug which is approved by the FDA. It has low
bioavailability, which is only 50%, in spite of its rapid absorption when orally administered …
bioavailability, which is only 50%, in spite of its rapid absorption when orally administered …
[HTML][HTML] Cod liver oil nano-structured lipid carriers (Cod-NLCs) as a promising platform for nose to brain delivery: Preparation, in vitro optimization, ex vivo cytotoxicity …
Nano-structured lipid carriers containing zopiclone were prepared as a targeted drug
delivery system to convey zopiclone directly to brain via nasal route. Nano-structured lipid …
delivery system to convey zopiclone directly to brain via nasal route. Nano-structured lipid …
Solid lipid-based nanoparticulate system for sustained release and enhanced in-vitro cytotoxic effect of 5-fluorouracil on skin Melanoma and squamous cell …
The present study aimed to prepare solid lipid-based nanoparticles (SLNs) using Precirol®
ATO 5 as solid lipid and Poloxamer 188 and Tween 80 as surfactant and co-surfactant …
ATO 5 as solid lipid and Poloxamer 188 and Tween 80 as surfactant and co-surfactant …