Metabolic engineering: methodologies and applications

MJ Volk, VG Tran, SI Tan, S Mishra, Z Fatma… - Chemical …, 2022 - ACS Publications
Metabolic engineering aims to improve the production of economically valuable molecules
through the genetic manipulation of microbial metabolism. While the discipline is a little over …

Flavonoid biosynthetic pathways in plants: Versatile targets for metabolic engineering

SM Nabavi, D Šamec, M Tomczyk, L Milella… - Biotechnology …, 2020 - Elsevier
Plants, fungi, and microorganisms are equipped with biosynthesis machinery for producing
thousands of secondary metabolites. These compounds have important functions in nature …

Application of different types of CRISPR/Cas-based systems in bacteria

Z Liu, H Dong, Y Cui, L Cong, D Zhang - Microbial cell factories, 2020 - Springer
As important genome editing tools, CRISPR/Cas systems, especially those based on type II
Cas9 and type V Cas12a, are widely used in genetic and metabolic engineering of bacteria …

Escherichia coli as a host for metabolic engineering

S Pontrelli, TY Chiu, EI Lan, FYH Chen, P Chang… - Metabolic …, 2018 - Elsevier
Over the past century, Escherichia coli has become one of the best studied organisms on
earth. Features such as genetic tractability, favorable growth conditions, well characterized …

Biosynthesis and regulation of anthocyanin pathway genes

L Sunil, NP Shetty - Applied Microbiology and Biotechnology, 2022 - Springer
Anthocyanins are the phenolic compounds responsible for coloring pigments in fruits and
vegetables. Anthocyanins offer a wide range of health benefits to human health. Their scope …

Metabolic engineering advances and prospects for amino acid production

VF Wendisch - Metabolic engineering, 2020 - Elsevier
Amino acid fermentation is one of the major pillars of industrial biotechnology. The multi-
billion USD amino acid market is rising steadily and is diversifying. Metabolic engineering is …

Research progress, challenges, and perspectives in microbial pigment production for industrial applications-A review

LJ Rather, SS Mir, SA Ganie, Q Li - Dyes and Pigments, 2023 - Elsevier
Microbial pigments are gaining more attention in recent times due to their versatile
applications in the pharmaceutical, food, cosmetic, and textile industries. The development …

[HTML][HTML] Anthocyanins, multi-functional natural products of industrial relevance: Recent biotechnological advances

T Belwal, G Singh, P Jeandet, A Pandey, L Giri… - Biotechnology …, 2020 - Elsevier
Anthocyanins, the color compounds of plants, are known for their wide applications in food,
nutraceuticals and cosmetic industry. The biosynthetic pathway of anthocyanins is well …

A fluoride-responsive genetic circuit enables in vivo biofluorination in engineered Pseudomonas putida

P Calero, DC Volke, PT Lowe, CH Gotfredsen… - Nature …, 2020 - nature.com
Fluorine is a key element in the synthesis of molecules broadly used in medicine, agriculture
and materials. Addition of fluorine to organic structures represents a unique strategy for …

Complete Biosynthesis of Anthocyanins Using E. coli Polycultures

JA Jones, VR Vernacchio, SM Collins, AN Shirke, Y **u… - MBio, 2017 - Am Soc Microbiol
Fermentation-based chemical production strategies provide a feasible route for the rapid,
safe, and sustainable production of a wide variety of important chemical products, ranging …