Leveraging artificial intelligence in the fight against infectious diseases
Despite advances in molecular biology, genetics, computation, and medicinal chemistry,
infectious disease remains an ominous threat to public health. Addressing the challenges …
infectious disease remains an ominous threat to public health. Addressing the challenges …
Next-generation sequencing: insights to advance clinical investigations of the microbiome
Next-generation sequencing (NGS) technology has advanced our understanding of the
human microbiome by allowing for the discovery and characterization of unculturable …
human microbiome by allowing for the discovery and characterization of unculturable …
Large-scale genome sequencing of mycorrhizal fungi provides insights into the early evolution of symbiotic traits
Mycorrhizal fungi are mutualists that play crucial roles in nutrient acquisition in terrestrial
ecosystems. Mycorrhizal symbioses arose repeatedly across multiple lineages of …
ecosystems. Mycorrhizal symbioses arose repeatedly across multiple lineages of …
The PATRIC Bioinformatics Resource Center: expanding data and analysis capabilities
Abstract The PathoSystems Resource Integration Center (PATRIC) is the bacterial
Bioinformatics Resource Center funded by the National Institute of Allergy and Infectious …
Bioinformatics Resource Center funded by the National Institute of Allergy and Infectious …
Surveillance of antimicrobial resistance in low-and middle-income countries: a scattered picture
Data on comprehensive population-based surveillance of antimicrobial resistance is lacking.
In low-and middle-income countries, the challenges are high due to weak laboratory …
In low-and middle-income countries, the challenges are high due to weak laboratory …
New insights from uncultivated genomes of the global human gut microbiome
The genome sequences of many species of the human gut microbiome remain unknown,
largely owing to challenges in cultivating microorganisms under laboratory conditions. Here …
largely owing to challenges in cultivating microorganisms under laboratory conditions. Here …
Improvements to PATRIC, the all-bacterial bioinformatics database and analysis resource center
Abstract The Pathosystems Resource Integration Center (PATRIC) is the bacterial
Bioinformatics Resource Center (https://www. patricbrc. org). Recent changes to PATRIC …
Bioinformatics Resource Center (https://www. patricbrc. org). Recent changes to PATRIC …
Functional and genomic variation between human-derived isolates of Lachnospiraceae reveals inter-and intra-species diversity
Bacteria belonging to the Lachnospiraceae family are abundant, obligate anaerobic
members of the microbiota in healthy humans. Lachnospiraceae impact their hosts by …
members of the microbiota in healthy humans. Lachnospiraceae impact their hosts by …
Fast automated reconstruction of genome-scale metabolic models for microbial species and communities
Genome-scale metabolic models are instrumental in uncovering operating principles of
cellular metabolism, for model-guided re-engineering, and unraveling cross-feeding in …
cellular metabolism, for model-guided re-engineering, and unraveling cross-feeding in …
DeepARG: a deep learning approach for predicting antibiotic resistance genes from metagenomic data
Background Growing concerns about increasing rates of antibiotic resistance call for
expanded and comprehensive global monitoring. Advancing methods for monitoring of …
expanded and comprehensive global monitoring. Advancing methods for monitoring of …