A review on arsenic carcinogenesis: epidemiology, metabolism, genotoxicity and epigenetic changes

Q Zhou, S ** - Regulatory Toxicology and Pharmacology, 2018 - Elsevier
Long-term exposure to arsenic (inorganic arsenic) is a world-wide environmental health
concern. Arsenic is classified as the Group 1 human carcinogen by the International Agency …

The HUman MicroNucleus Project—an international collaborative study on the use of the micronucleus technique for measuring DNA damage in humans

M Fenech, N Holland, WP Chang, E Zeiger… - Mutation Research …, 1999 - Elsevier
The International Collaborative Project on Micronucleus Frequency in Human Populations
(HUMN) was organized to collect data on micronucleus (MN) frequencies in different human …

High arsenic in rice is associated with elevated genotoxic effects in humans

M Banerjee, N Banerjee, P Bhattacharjee, D Mondal… - Scientific reports, 2013 - nature.com
Arsenic in drinking water may cause major deleterious health impacts including death.
Although arsenic in rice has recently been demonstrated to be a potential exposure route for …

Elevated exposures to polycyclic aromatic hydrocarbons and other organic mutagens in Ottawa firefighters participating in emergency, on-shift fire suppression

JLA Keir, US Akhtar, DMJ Matschke… - … science & technology, 2017 - ACS Publications
Occupational exposures to combustion emissions were examined in Ottawa Fire Service
(OFS) firefighters. Paired urine and dermal wipe samples (ie, pre-and post-event) as well as …

The chemopreventive effects of tea on human oral precancerous mucosa lesions

N Li, Z Sun, C Han, J Chen - Proceedings of the Society for …, 1999 - Wiley Online Library
A double‐blind intervention trial was conducted in patients with oral mucosa leukoplakia
using a mixed tea product developed by the authors. Fifty‐nine oral mucosa leukoplakia …

Use of the micronucleus assay with exfoliated epithelial cells as a biomarker for monitoring individuals at elevated risk of genetic damage and in chemoprevention …

BJ Majer, B Laky, S Knasmüller, F Kassie - Mutation Research/Reviews in …, 2001 - Elsevier
This review summarises the current database on the micronucleus (MN) assay with
exfoliated cells (MEC assay) and evaluates the predictive value of this model for the …

Cytogenetic effects in human exposure to arsenic

ME Gonsebatt, L Vega, AM Salazar, R Montero… - … Research/Reviews in …, 1997 - Elsevier
The cytogenetic effects of arsenic exposure were studied among rural populations that live
in the same geographical area and have similar socioeconomic status, but different degree …

Khat (Catha edulis) consumption causes genotoxic effects in humans

F Kassie, F Darroudi, M Kundi… - … journal of cancer, 2001 - Wiley Online Library
We used the micronucleus (MN) test to determine the genetic damage caused by khat, a
widely consumed psychostimulant plant, in exfoliated cells of volunteers who chewed the …

The use of the micronucleus test on exfoliated cells to identify anti-clastogenic action in humans: a biological marker for the efficacy of chemopreventive agents

MP Rosin - … Research/Fundamental and Molecular Mechanisms of …, 1992 - Elsevier
Laboratory and epidemiological studies support the hypothesis that cancer incidence in
human populations can be reduced by supplementing high-risk individuals with …

Increased micronuclei in exfoliated bladder cells of individuals who chronically ingest arsenic-contaminated water in Nevada.

ML Warner, LE Moore, MT Smith, DA Kalman… - … , biomarkers & prevention …, 1994 - AACR
It is well established that inorganic arsenic is causally associated with lung cancer via
inhalation and skin cancer via ingestion. Epidemiological evidence based on studies in …