Cells migrate in multiple different ways depending on their environment, which includes the
extracellular matrix composition, interactions with other cells, and chemical stimuli. For all …

Summary 3D amoeboid cell migration is central to many developmental and disease-related
processes such as cancer metastasis. Here, we identify a unique prototypic amoeboid cell …

Vertebrate embryos establish their primary body axis in a conserved progressive fashion
from the anterior to the posterior. During this process, a posteriorly localized …

MicroRNA-200c (miR-200c) has been shown to suppress epithelial-mesenchymal transition
(EMT), which is attributed mainly to targeting of ZEB1/ZEB2, repressors of the cell-cell …

The vertebrate body forms in an anterior-to-posterior progression, driven by a population of
undifferentiated cells at the posterior-most end of the embryo. Recent studies have …

Mesoderm induction begins during gastrulation. Recent evidence from several vertebrate
species indicates that mesoderm induction continues after gastrulation in neuromesodermal …

The vertebrate body forms from a multipotent stem cell-like progenitor population that
progressively contributes newly differentiated cells to the most posterior end of the embryo …

Somites are formed from the presomitic mesoderm (PSM) and give rise to the axial skeleton
and skeletal muscles. The PSM is dynamic; somites are generated at the anterior end, while …

Anterior to posterior growth of the vertebrate body is fueled by a posteriorly located
population of bipotential neuro-mesodermal progenitor cells. These progenitors have a …

The sculpting of germ layers during gastrulation relies on the coordinated migration of
progenitor cells, yet the cues controlling these long-range directed movements remain …