Understanding COVID-19-associated coagulopathy

EM Conway, N Mackman, RQ Warren… - Nature Reviews …, 2022 - nature.com
Abstract COVID-19-associated coagulopathy (CAC) is a life-threatening complication of
SARS-CoV-2 infection. However, the underlying cellular and molecular mechanisms driving …

Therapeutic advances in COVID-19

N Murakami, R Hayden, T Hills, H Al-Samkari… - Nature Reviews …, 2023 - nature.com
Over 2 years have passed since the start of the COVID-19 pandemic, which has claimed
millions of lives. Unlike the early days of the pandemic, when management decisions were …

SARS-CoV-2, COVID-19 and the aging immune system

JM Bartleson, D Radenkovic, AJ Covarrubias… - Nature aging, 2021 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic is a global health threat with
particular risk for severe disease and death in older adults and in adults with age-related …

IL-6 in inflammation, autoimmunity and cancer

T Hirano - International immunology, 2021 - academic.oup.com
IL-6 is involved both in immune responses and in inflammation, hematopoiesis, bone
metabolism and embryonic development. IL-6 plays roles in chronic inflammation (closely …

COVID-19 and diabetes mellitus: from pathophysiology to clinical management

S Lim, JH Bae, HS Kwon, MA Nauck - Nature Reviews Endocrinology, 2021 - nature.com
Initial studies found increased severity of coronavirus disease 2019 (COVID-19), caused by
infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), in patients …

COVID-19: breaking down a global health crisis

SI Mallah, OK Ghorab, S Al-Salmi, OS Abdellatif… - Annals of clinical …, 2021 - Springer
Abstract Coronavirus disease 2019 (COVID-19) is the second pandemic of the twenty-first
century, with over one-hundred million infections and over two million deaths to date. It is a …

Mechanisms of SARS-CoV-2 transmission and pathogenesis

AG Harrison, T Lin, P Wang - Trends in immunology, 2020 - cell.com
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) marks
the third highly pathogenic coronavirus to spill over into the human population. SARS-CoV-2 …

Mucosal immune responses to infection and vaccination in the respiratory tract

RC Mettelman, EK Allen, PG Thomas - Immunity, 2022 - cell.com
The lungs are constantly exposed to inhaled debris, allergens, pollutants, commensal or
pathogenic microorganisms, and respiratory viruses. As a result, innate and adaptive …

COVID-19 and cardiovascular disease: from basic mechanisms to clinical perspectives

M Nishiga, DW Wang, Y Han, DB Lewis… - Nature Reviews …, 2020 - nature.com
Abstract Coronavirus disease 2019 (COVID-19), caused by a strain of coronavirus known as
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a global …

Role of angiotensin-converting enzyme 2 (ACE2) in COVID-19

W Ni, X Yang, D Yang, J Bao, R Li, Y **ao, C Hou… - Critical Care, 2020 - Springer
An outbreak of pneumonia caused by severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) that started in Wuhan, China, at the end of 2019 has become a global …