NMR metabolomics methods for investigating disease

GA Nagana Gowda, D Raftery - Analytical chemistry, 2023 - ACS Publications
The field of metabolomics continues to grow exponentially as it contributes significantly to
numerous disciplines, including biomedicine, pharmacology, drug development, and …

Uneven metabolic and lipidomic profiles in recovered COVID‐19 patients as investigated by plasma NMR metabolomics

M Bizkarguenaga, C Bruzzone… - NMR in …, 2022 - Wiley Online Library
COVID‐19 is a systemic infectious disease that may affect many organs, accompanied by a
measurable metabolic dysregulation. The disease is also associated with significant …

Unlocking secrets: lipid metabolism and lipid droplet crucial roles in SARS-CoV-2 infection and the immune response

VC Soares, SSG Dias, JC Santos… - Journal of Leukocyte …, 2024 - academic.oup.com
Lipid droplets (LDs) are crucial for maintaining lipid and energy homeostasis within cells.
LDs are highly dynamic organelles that present a phospholipid monolayer rich in neutral …

Reinforcing the Evidence of Mitochondrial Dysfunction in Long COVID Patients Using a Multiplatform Mass Spectrometry-Based Metabolomics Approach

S Martínez, OE Albóniga… - Journal of Proteome …, 2024 - ACS Publications
Despite the recent and increasing knowledge surrounding COVID-19 infection, the
underlying mechanisms of the persistence of symptoms for a long time after the acute …

Cross-Validation of Metabolic Phenotypes in SARS-CoV-2 Infected Subpopulations Using Targeted Liquid Chromatography–Mass Spectrometry (LC-MS)

L Whiley, NG Lawler, AX Zeng, A Lee… - Journal of proteome …, 2024 - ACS Publications
To ensure biological validity in metabolic phenoty**, findings must be replicated in
independent sample sets. Targeted workflows have long been heralded as ideal platforms …

Starve a cold or feed a fever? Identifying cellular metabolic changes following infection and exposure to SARS-CoV-2

EK Loveday, H Welhaven, AE Erdogan, KS Hain… - PloS one, 2025 - journals.plos.org
Viral infections induce major shifts in cellular metabolism elicited by active viral replication
and antiviral responses. For the virus, harnessing cellular metabolism and evading changes …