[PDF][PDF] Background document on the Janssen Ad26. COV2. S (COVID-19) vaccine: background document to the WHO Interim recommendations for use of Ad26. COV2 …

World Health Organization - 2021 - apps.who.int
Background This background document was prepared by the Strategic Advisory Group of
Experts (SAGE) on Immunization Working Group on COVID-19 Vaccines to inform the …

[HTML][HTML] Immunogenicity and efficacy of COVID-19 vaccines in people living with HIV: a systematic review and meta-analysis

J Yin, Y Chen, Y Li, C Wang, X Zhang - International Journal of Infectious …, 2022 - Elsevier
Objectives Available data show that COVID-19 vaccines may be less effective in people
living with HIV (PLWH) who are at increased risk for severe COVID-19. This meta-analysis …

Optimization of anti-SARS-CoV-2 neutralizing antibody therapies: roadmap to improve clinical effectiveness and implementation

K van der Straten, MJ van Gils, SW de Taeye… - Frontiers in Medical …, 2022 - frontiersin.org
One of the major breakthroughs to combat the current Coronavirus Disease 2019 (COVID-
19) pandemic has been the development of highly effective vaccines against the Severe …

[HTML][HTML] Protection from SARS-CoV-2 Delta one year after mRNA-1273 vaccination in rhesus macaques coincides with anamnestic antibody response in the lung

M Gagne, KS Corbett, BJ Flynn, KE Foulds, DA Wagner… - Cell, 2022 - cell.com
Summary mRNA-1273 vaccine efficacy against SARS-CoV-2 Delta wanes over time;
however, there are limited data on the impact of durability of immune responses on …

From a recombinant key antigen to an accurate, affordable serological test: Lessons learnt from COVID-19 for future pandemics

RGF Alvim, TM Lima, DAS Rodrigues, FF Marsili… - Biochemical …, 2022 - Elsevier
Serological tests detect antibodies generated by infection or vaccination, and are
indispensable tools along different phases of a pandemic, from early monitoring of pathogen …

Forward and reverse translational approaches to predict efficacy of neutralizing respiratory syncytial virus (RSV) antibody prophylaxis

BM Maas, J Lommerse, N Plock, RA Railkar… - …, 2021 - thelancet.com
Background Neutralizing mAbs can prevent communicable viral diseases. MK-1654 is a
respiratory syncytial virus (RSV) F glycoprotein neutralizing monoclonal antibody (mAb) …

Comparative analysis of spike-specific IgG Fc glycoprofiles elicited by adenoviral, mRNA, and protein-based SARS-CoV-2 vaccines

J Van Coillie, T Pongracz, T Šuštić, W Wang, J Nouta… - Iscience, 2023 - cell.com
IgG antibodies are important mediators of vaccine-induced immunity through complement-
and Fc receptor-dependent effector functions. Both are influenced by the composition of the …

Defining the determinants of protection against SARS-CoV-2 infection and viral control in a dose-down Ad26. CoV2. S vaccine study in nonhuman primates

DY Zhu, MJ Gorman, D Yuan, J Yu, NB Mercado… - PLoS …, 2022 - journals.plos.org
Despite the rapid creation of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-
CoV-2) vaccines, the precise correlates of immunity against severe Coronavirus Disease …

Age-related heterogeneity in neutralising antibody responses to SARS-CoV-2 following BNT162b2 vaccination

DA Collier, IATM Ferreira, R Datir, B Meng… - MedRxiv, 2021 - medrxiv.org
Background Vaccines remain the cornerstone for containing the SARS-CoV-2 pandemic.
mRNA vaccines provide protection in clinical trials using a two-dose approach, separated by …

A measles-vectored vaccine candidate expressing prefusion-stabilized SARS-CoV-2 spike protein brought to phase I/II clinical trials: protection of African green …

S Nambulli, N Escriou, LJ Rennick, MJ Demers… - Journal of …, 2024 - Am Soc Microbiol
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged at the end of
2019 and is responsible for the largest human pandemic in 100 years. Thirty-four vaccines …