Diabetes represents a major public health concern with a considerable impact on human life
and healthcare expenditures. It is now well established that diabetes is characterized by a …

Skeletal muscle, which accounts for approximately 40% of total body weight, is one of the
most dynamic and plastic tissues in the human body and plays a vital role in movement …

Aims Patients with heart failure and reduced ejection fraction (HFrEF) exhibit skeletal muscle
pathology, which contributes to symptoms and decreased quality of life. Sodium–glucose …

The purpose of this review is to describe the present evidence for exercise and nutritional
interventions as potential contributors in the treatment of sarcopenia and frailty (ie muscle …

Background Exercise is beneficial for muscle atrophy. Peroxisome proliferator-activated
receptor gamma (PPARγ) and microRNA-29b (miR-29b) have been reported to be …

Aims Reduced skeletal muscle mass is a major component of sarcopenia, associated with
impaired exercise capacity and poor prognosis in patients with heart failure (HF) …

Weight loss has been associated with significant improvements in glycemic control, quality
of life, and comorbidities in people with type 2 diabetes. Furthermore, achieving diabetes …

Frailty is defined as 'a state of increased vulnerability to endogenous and exogenous
stressors, due to age-related declines in physiologic reserve and function across multiple …

Introduction: Protein-energy waste (PEW) is a common complication in patients with chronic
kidney disease (CKD), among which skeletal muscle atrophy is one of the most important …

Skeletal muscle makes up almost half the body weight of heathy individuals and is involved
in several vital functions, including breathing, thermogenesis, metabolism, and locomotion …