The evolving value of older biomarkers in the clinical diagnosis of pediatric sepsis

PPC Lim, DJ Bondarev, AM Edwards, CM Hoyen… - Pediatric …, 2023 - nature.com
Sepsis remains the leading cause of childhood mortality worldwide. The evolving definition
of pediatric sepsis is extrapolated from adult studies. Although lacking formal validation in …

Sepsis and septic shock

PJ Maloney - Emergency Medicine Clinics, 2013 - emed.theclinics.com
Infectious diseases have been a leading cause of death throughout the history of the human
race, but only recently have we begun to understand their effects on the body. Ancient Greek …

The utility of early lactate testing in undifferentiated pediatric systemic inflammatory response syndrome

HF Scott, AJ Donoghue, DF Gaieski… - Academic …, 2012 - Wiley Online Library
Objectives Failure to recognize shock contributes to inadequate early resuscitation in many
children with sepsis. Serum lactate levels are used to identify adult patients with septic …

Elevated arterial lactate level as an independent risk factor for pancreatic infection in moderately severe acute pancreatitis

W Shu, J Wan, J Chen, W He, Y Zhu, N Lu, L **a - Pancreatology, 2019 - Elsevier
Purpose The present study aimed to research the relationships between arterial lactate
levels and pancreatic infection in moderately severe acute pancreatitis. Methods This study …

Point-of-care C reactive protein to identify serious infection in acutely ill children presenting to hospital: prospective cohort study

JY Verbakel, MB Lemiengre… - Archives of Disease in …, 2018 - adc.bmj.com
Objective Acute infection is the most common presentation of children to hospital. A minority
of these infections are serious, but early recognition and adequate management are …

Serum lactate is associated with increased illness severity in immunocompromised pediatric hematology oncology patients presenting to the emergency department …

LR Slatnick, K Miller, HF Scott, M Loi… - Frontiers in …, 2022 - frontiersin.org
Introduction Determining which febrile pediatric hematology/oncology (PHO) patients will
decompensate from severe infection is a significant challenge. Serum lactate is a well …

Increased Constituent Ratios of Klebsiella sp., Acinetobacter sp., and Streptococcus sp. and a Decrease in Microflora Diversity May Be Indicators of Ventilator …

W Lu, J Yu, Q Ai, D Liu, C Song, L Li - PloS one, 2014 - journals.plos.org
Ventilator-associated pneumonia (VAP) is a common complication and cause of death in
neonates on mechanical ventilation. However, it is difficult to define the causes of VAP. To …

Lab-score is a valuable predictor of serious bacterial infection in infants admitted to hospital

J Markic, T Kovacevic, V Krzelj, N Bosnjak… - Wiener klinische …, 2015 - Springer
Parents frequently bring their children to the Emergency Department (ED) because of the
fever without apparent source (FWAS). To avoid possible complications, it is important to …

Association between initial emergency department lactate and use of vasoactive medication in children with septic shock

MJ Miescier, RD Lane, X Sheng… - Pediatric Emergency …, 2019 - journals.lww.com
Objectives Current guidelines emphasize early recognition of pediatric septic shock using
clinical examination findings. Elevated serum lactate has been associated with increased …

Accuracy, user-friendliness and usefulness of the Cobas h232 point-of-care test for NT-proBNP in primary care

C Hex, M Smeets, J Penders, V Van Hoof… - Journal of clinical …, 2018 - jcp.bmj.com
Aims N-terminal pro-B-type natriuretic peptide (NT-proBNP) has been shown to be useful for
ruling out heart failure in primary care. In this study, we examined the accuracy of the Cobas …