Atrial fibrillation (AF) has become the pre-dominant arrhythmia worldwide and is associated
with high morbidity and mortality. Its pathogenesis is intricately linked to the deleterious …

Clonal hematopoiesis of indeterminate potential (CHIP) is a well-studied phenomenon in
hematologic malignancies. With advancements in gene sampling and analysis and the use …

Introduction Recent work has revealed that clonal hematopoiesis (CH) is associated with a
higher risk of numerous age-related diseases, including ischemic stroke, however little is …

Clonal hematopoiesis (CH) typically refers to the clonal expansion of hematopoietic stem
cells (HSCs) due to genetic mutations, serving as the pathogenic basis for various diseases …

In heart failure (HF) patients undergoing cardiac surgery, an increased activity of
mechanisms related to cardiac remodeling may determine a higher risk of postoperative …

Mosaic loss of chromosome Y (mLOY), the most common somatic mutation, prompts fibrotic
heart diseases. We hypothesized that it accelerates atrial fibrillation (AF) and contributes to …

The aberrant activation of the nucleotide-binding oligomerization domain-like receptor family
pyrin domain-containing protein 3 (NLRP3) inflammasome has been implicated in the …

Inflammatory cytokines, including interleukin 6 (IL6), are associated with ion channel
remodeling and enhance the propensity to alterations in cardiac rhythm generation and …

Clonal hematopoiesis (CH) is associated with an increased risk of develo** myeloid
neoplasms (MNs) such as myelodysplastic neoplasm (MDS) and acute myeloid leukemia …

Clonal hematopoiesis of indeterminate potential (CHIP) is an age-related phenomenon in
which somatic mutations lead to clonal expansion of hematopoietic stem cells (HSCs) …