Social status alters immune regulation and response to infection in macaques

N Snyder-Mackler, J Sanz, JN Kohn, JF Brinkworth… - Science, 2016 - science.org
Social status is one of the strongest predictors of human disease risk and mortality, and it
also influences Darwinian fitness in social mammals more generally. To understand the …

Re-wilding Model Organisms: Opportunities to test causal mechanisms in social determinants of health and aging

MN Zipple, CC Vogt, MJ Sheehan - Neuroscience & Biobehavioral …, 2023 - Elsevier
Social experiences are strongly associated with individuals' health, aging, and survival in
many mammalian taxa, including humans. Despite their role as models of many other …

Evolutionary approaches in aging research

ME Thompson - Cold Spring Harbor Perspectives …, 2022 - perspectivesinmedicine.cshlp.org
While evolutionary explanations for aging have been widely acknowledged, the application
of evolutionary principles to the practice of aging research has, until recently, been limited …

Social status alters chromatin accessibility and the gene regulatory response to glucocorticoid stimulation in rhesus macaques

N Snyder-Mackler, J Sanz, JN Kohn… - Proceedings of the …, 2019 - National Acad Sciences
Low social status is an important predictor of disease susceptibility and mortality risk in
humans and other social mammals. These effects are thought to stem in part from …

Distinct gene regulatory signatures of dominance rank and social bond strength in wild baboons

JA Anderson, AJ Lea, TN Voyles… - … of the Royal …, 2022 - royalsocietypublishing.org
The social environment is a major determinant of morbidity, mortality and Darwinian fitness
in social animals. Recent studies have begun to uncover the molecular processes …

Social buffering of stress–Physiological and ethological perspectives

A Wu - Applied Animal Behaviour Science, 2021 - Elsevier
Research into the impact of sociality on stress has largely focused on social factors as
stressors, but it is now well-known that the mere presence of a conspecific can reduce an …

Social dominance differentially alters gene expression in the medial prefrontal cortex without affecting adult hippocampal neurogenesis or stress and anxiety‐like …

A Pallé, C Zorzo, VE Luskey, KR McGreevy… - The FASEB …, 2019 - Wiley Online Library
Social hierarchies are crucial for a group's survival and can influence the way an individual
behaves and relates to a given social context. The study of social rank has been classically …

Immune cell composition varies by age, sex and exposure to social adversity in free-ranging Rhesus Macaques

MRS Rosado, N Marzan-Rivera, MM Watowich… - GeroScience, 2024 - Springer
Increasing age is associated with dysregulated immune function and increased
inflammation—patterns that are also observed in individuals exposed to chronic social …

Agonism and grooming behaviour explain social status effects on physiology and gene regulation in rhesus macaques

ND Simons, V Michopoulos… - … of the Royal …, 2022 - royalsocietypublishing.org
Variation in social status predicts molecular, physiological and life-history outcomes across
a broad range of species, including our own. Experimental studies indicate that some of …

Sex differences in dominance relationships in Syrian hamsters

CJ Whitten, MK Hooker, AN Wells, JN Kearney… - Physiology & …, 2023 - Elsevier
Dominance relationships are identified by changes in agonistic behavior toward specific
individuals. While there are considerable individual and species differences in dominance …