Extracellular signals regulate the biogenesis of extracellular vesicles

Y **, L Ma, W Zhang, W Yang, Q Feng, H Wang - Biological Research, 2022 - Springer
Extracellular vesicles (EVs) are naturally released membrane vesicles that act as carriers of
proteins and RNAs for intercellular communication. With various biomolecules and specific …

Exocytosis of Nanoparticles: A Comprehensive Review

J Liu, YY Liu, CS Li, A Cao, H Wang - Nanomaterials, 2023 - mdpi.com
Both biomedical applications and safety assessments of manufactured nanomaterials
require a thorough understanding of the interaction between nanomaterials and cells …

Extracellular vesicles from alveolar macrophages harboring phagocytosed methicillin-resistant Staphylococcus aureus induce necroptosis

S Bai, X Wen, B Li, R Hu, J Yang, Q Yu, X Zeng, H Feng… - Cell Reports, 2024 - cell.com
Methicillin-resistant Staphylococcus aureus (MRSA) infection, a major cause of hospital-and
community-acquired pneumonia, still has a high mortality rate. Extracellular vesicles (EVs) …

Systematic compositional analysis of exosomal extracellular vesicles produced by cells undergoing apoptosis, necroptosis and ferroptosis

B Cappe, M Vadi, E Sack, L Wacheul… - Journal of …, 2023 - Wiley Online Library
Formation of extracellular vesicles (EVs) has emerged as a novel paradigm in cell‐to‐cell
communication in health and disease. EVs are notably produced during cell death but it had …

A guide to the expanding field of extracellular vesicles and their release in regulated cell death programs

B Cappe, P Vandenabeele, FB Riquet - The FEBS Journal, 2024 - Wiley Online Library
Homeostasis disruption is visible at the molecular and cellular levels and may often lead to
cell death. This vital process allows us to maintain the more extensive system's integrity by …

Necroptosis in CNS diseases: Focus on astrocytes

EV Mitroshina, M Saviuk, MV Vedunova - Frontiers in Aging …, 2023 - frontiersin.org
In the last few years, necroptosis, a recently described type of cell death, has been reported
to play an important role in the development of various brain pathologies. Necroptosis is a …

Micro Trojan horses: Engineering extracellular vesicles crossing biological barriers for drug delivery

B Zeng, Y Li, J **a, Y **ao, N Khan… - Bioengineering & …, 2024 - Wiley Online Library
The biological barriers of the body, such as the blood–brain, placental, intestinal, skin, and
air‐blood, protect against invading viruses and bacteria while providing necessary physical …

Yin-Yang: two sides of extracellular vesicles in inflammatory diseases

B Zeng, Y Li, N Khan, A Su, Y Yang, P Mi… - Journal of …, 2024 - Springer
Abstract The concept of Yin-Yang, originating in ancient Chinese philosophy, symbolizes
two opposing but complementary forces or principles found in all aspects of life. This …

The uptake of extracellular vesicles: research progress in cancer drug resistance and beyond

L Qian, P Chen, S Zhang, Z Wang, Y Guo… - Drug Resistance …, 2025 - Elsevier
Extracellular vesicles (EVs) are heterogeneous vesicles released by donor cells that can be
taken up by recipient cells, thus inducing cellular phenotype changes. Since their discovery …

Proteomic characterization of extracellular vesicles in programmed cell death

VW Xue, SCC Wong, H Zhao, WCS Cho - Proteomics, 2024 - Wiley Online Library
Programmed cell death (PCD) is a fundamental biological process that plays a critical role in
cell development, differentiation, and homeostasis. The secretion and uptake of extracellular …