[HTML][HTML] Molecular and cellular mechanisms of action of cannabidiol
Cannabidiol (CBD) is the primary non-psychoactive chemical from Cannabis Sativa, a plant
used for centuries for both recreational and medicinal purposes. CBD lacks the psychotropic …
used for centuries for both recreational and medicinal purposes. CBD lacks the psychotropic …
The polypharmacological effects of cannabidiol
Cannabidiol (CBD) is a major phytocannabinoid present in Cannabis sativa (Linneo, 1753).
This naturally occurring secondary metabolite does not induce intoxication or exhibit the …
This naturally occurring secondary metabolite does not induce intoxication or exhibit the …
Secondary metabolites profiled in cannabis inflorescences, leaves, stem barks, and roots for medicinal purposes
D **, K Dai, Z **e, J Chen - Scientific reports, 2020 - nature.com
Cannabis research has historically focused on the most prevalent cannabinoids. However,
extracts with a broad spectrum of secondary metabolites may have increased efficacy and …
extracts with a broad spectrum of secondary metabolites may have increased efficacy and …
Diversity of molecular targets and signaling pathways for CBD
Cannabidiol (CBD) is the second most abundant component of the Cannabis plant and is
known to have effects distinct from Δ9‐tetrahydrocannabinol (THC). Many studies that …
known to have effects distinct from Δ9‐tetrahydrocannabinol (THC). Many studies that …
[HTML][HTML] Cannabidiol: a potential new alternative for the treatment of anxiety, depression, and psychotic disorders
MS García-Gutiérrez, F Navarrete, A Gasparyan… - Biomolecules, 2020 - mdpi.com
The potential therapeutic use of some Cannabis sativa plant compounds has been attracting
great interest, especially for managing neuropsychiatric disorders due to the relative lack of …
great interest, especially for managing neuropsychiatric disorders due to the relative lack of …
Cannabidiol modulates serotonergic transmission and reverses both allodynia and anxiety-like behavior in a model of neuropathic pain
Clinical studies indicate that cannabidiol (CBD), the primary nonaddictive component of
cannabis that interacts with the serotonin (5-HT) 1A receptor, may possess analgesic and …
cannabis that interacts with the serotonin (5-HT) 1A receptor, may possess analgesic and …
Immune responses regulated by cannabidiol
JM Nichols, BLF Kaplan - Cannabis and cannabinoid research, 2020 - liebertpub.com
Introduction: Cannabidiol (CBD) as Epidiolex®(GW Pharmaceuticals) was recently
approved by the US Food and Drug Administration (FDA) to treat rare forms of epilepsy in …
approved by the US Food and Drug Administration (FDA) to treat rare forms of epilepsy in …
Translational investigation of the therapeutic potential of cannabidiol (CBD): toward a new age
Background: Among the many cannabinoids in the cannabis plant, cannabidiol (CBD) is a
compound that does not produce the typical subjective effects of marijuana. Objectives: The …
compound that does not produce the typical subjective effects of marijuana. Objectives: The …
[HTML][HTML] Cannabidiol as a potential treatment for anxiety disorders
EM Blessing, MM Steenkamp, J Manzanares… - …, 2015 - Elsevier
Cannabidiol (CBD), a Cannabis sativa constituent, is a pharmacologically broad-spectrum
drug that in recent years has drawn increasing interest as a treatment for a range of …
drug that in recent years has drawn increasing interest as a treatment for a range of …
Cannabidiol for the treatment of cannabis use disorder: a phase 2a, double-blind, placebo-controlled, randomised, adaptive Bayesian trial
Background A substantial and unmet clinical need exists for pharmacological treatment of
cannabis use disorders. Cannabidiol could offer a novel treatment, but it is unclear which …
cannabis use disorders. Cannabidiol could offer a novel treatment, but it is unclear which …