Some aspects of glucose homeostasis are regulated differently in males and females. This
review discusses the most fundamental gender differences in glucose homeostasis and …

The twin epidemic of obesity and diabetes is a major crisis globally. Several epidemiologic
studies reveal the parallel escalation of obesity and diabetes. The term 'diabesity'expresses …

Objective In men, androgen deprivation contributes to the development of metabolic
syndrome and type 2 diabetes (T2D). In women, androgen excess predisposes to insulin …

Sex hormone binding globulin (SHBG) is a glycoprotein composed of two 373‐amino‐acid
subunits. The SHBG gene and a promotor region have been identified. The SHBG receptor …

Sex hormone-binding globulin (SHBG) has emerged as one of the multiple genetic and
environmental factors that potentially contribute to the pathophysiology of type 2 diabetes …

The principle steroidal androgens are testosterone and its metabolite 5α-
dihydrotestosterone (DHT), which is converted from testosterone by the enzyme 5α …

Obesity is one of the epidemics of our era. Its prevalence is higher than 30% in the US and it
is estimated to increase by 50% in 2030. Obesity is associated with a higher risk of all-cause …

Heart disease remains a major cause of death among women in the United States. 1 In
2008, 1 in 31 deaths in US women was attributable to breast cancer, whereas 1 in 6.6 …

Androgens are essential for the development and maintenance of male reproductive tissues
and sexual function and for overall health and well being. Testosterone, the predominant …

Introduction Endocrine changes during aging as well as endocrine disorders may either
directly or indirectly modulate female sexual function by altering sex hormones, or by …