Antibiotic resistance in Pseudomonas aeruginosa–Mechanisms, epidemiology and evolution

J Botelho, F Grosso, L Peixe - Drug resistance updates, 2019 - Elsevier
Antibiotics are powerful drugs used in the treatment of bacterial infections. The inappropriate
use of these medicines has driven the dissemination of antibiotic resistance (AR) in most …

The physiology and genetics of bacterial responses to antibiotic combinations

R Roemhild, T Bollenbach, DI Andersson - Nature Reviews …, 2022 - nature.com
Several promising strategies based on combining or cycling different antibiotics have been
proposed to increase efficacy and counteract resistance evolution, but we still lack a deep …

Antibiotic resistance: turning evolutionary principles into clinical reality

DI Andersson, NQ Balaban, F Baquero… - FEMS microbiology …, 2020 - academic.oup.com
Antibiotic resistance is one of the major challenges facing modern medicine worldwide. The
past few decades have witnessed rapid progress in our understanding of the multiple factors …

[HTML][HTML] Soil biota, antimicrobial resistance and planetary health

YG Zhu, Y Zhao, D Zhu, M Gillings, J Penuelas… - Environment …, 2019 - Elsevier
The concept of planetary health acknowledges the links between ecosystems, biodiversity
and human health and well-being. Soil, the critical component of the interconnected …

[HTML][HTML] Drug repurposing for next-generation combination therapies against multidrug-resistant bacteria

Y Liu, Z Tong, J Shi, R Li, M Upton, Z Wang - Theranostics, 2021 - ncbi.nlm.nih.gov
Antimicrobial resistance has been a global health challenge that threatens our ability to
control and treat life-threatening bacterial infections. Despite ongoing efforts to identify new …

Tackling antibiotic resistance with compounds of natural origin: A comprehensive review

FJ Álvarez-Martínez, E Barrajón-Catalán, V Micol - Biomedicines, 2020 - mdpi.com
Drug-resistant bacteria pose a serious threat to human health worldwide. Current antibiotics
are losing efficacy and new antimicrobial agents are urgently needed. Living organisms are …

A review of chemical signaling pathways in the quorum sensing circuit of Pseudomonas aeruginosa

K Vadakkan, AK Ngangbam, K Sathishkumar… - International Journal of …, 2024 - Elsevier
Pseudomonas aeruginosa, an increasingly common competitive and biofilm organism in
healthcare infection with sophisticated, interlinked and hierarchic quorum systems (Las, Rhl …

Nanophysical antimicrobial strategies: a rational deployment of nanomaterials and physical stimulations in combating bacterial infections

B Jia, X Du, W Wang, Y Qu, X Liu, M Zhao… - Advanced …, 2022 - Wiley Online Library
The emergence of bacterial resistance due to the evolution of microbes under antibiotic
selection pressure, and their ability to form biofilm, has necessitated the development of …

[HTML][HTML] Variation of antibiotic resistome during commercial livestock manure composting

M Zhang, LY He, YS Liu, JL Zhao, JN Zhang… - Environment …, 2020 - Elsevier
Composting has been widely used to turn livestock manure into organic fertilizer. However,
livestock manure contains various contaminants including antibiotics and antibiotic …

Antimicrobial Resistance in Escherichia coli Strains Isolated from Humans and Pet Animals

N Puvača, R de Llanos Frutos - Antibiotics, 2021 - mdpi.com
Throughout scientific literature, we can find evidence that antimicrobial resistance has
become a big problem in the recent years on a global scale. Public healthcare systems all …