The discovery of the role of non-coding RNAs (ncRNAs) in the onset and progression of
malignancies is a promising frontier of cancer genetics. It is clear that ncRNAs are …

Dozens of normalization methods for correcting experimental variation and bias in high-
throughput expression data have been developed during the last two decades. Up to 23 …

Background Hypoxia-related genes are demonstrated to correlate with the prognosis of
various cancers. However, the role of hypoxia-related long non-coding RNAs (HRLs) in …

Objective: Colorectal cancer (CRC) is one of the common malignant tumors worldwide.
Chromobox (CBX) family proteins are important components of epigenetic regulation …

Background Recent studies have revealed the significant roles of immune-related long
noncoding RNAs (lncRNAs) in cancer development and progression. The identification of …

Gastric cancer (GC) remains a leading cause of cancer-related mortality in the United States
and China, there is an urgent need to discover novel non-invasive biomarkers for the early …

Purpose. Colorectal cancer is one of the most common malignant primary tumors, prone to
metastasis, and associated with a poor prognosis. As autophagy is closely related to the …

Alzheimer's disease (AD), a degenerative disease of the central nervous system, is the most
common form of dementia in old age. The complexity and behavior of circular RNA …

The advances in single-cell RNA sequencing (scRNA-seq) technologies enable the
characterization of transcriptomic profiles at the cellular level and demonstrate great promise …

Background Colorectal cancer (CRC) is a common malignant tumor with high metastatic and
recurrent rates. This study probes the effect and mechanism of long non-coding RNA …