Tailoring materials for modulation of macrophage fate
Human immune system acts as a pivotal role in the tissue homeostasis and disease
progression. Immunomodulatory biomaterials that can manipulate innate immunity and …
progression. Immunomodulatory biomaterials that can manipulate innate immunity and …
Macrophage cell membrane‐cloaked nanoplatforms for biomedical applications
J Lopes, D Lopes, M Pereira‐Silva, D Peixoto… - Small …, 2022 - Wiley Online Library
Biomimetic approaches utilize natural cell membrane‐derived nanovesicles to camouflage
nanoparticles to circumvent some limitations of nanoscale materials. This emergent cell …
nanoparticles to circumvent some limitations of nanoscale materials. This emergent cell …
Engineering cells for precision drug delivery: New advances, clinical translation, and emerging strategies
Cells have emerged as a promising new form of drug delivery carriers owing to their
distinguished advantages such as naturally bypassing immune recognition, intrinsic …
distinguished advantages such as naturally bypassing immune recognition, intrinsic …
Augmenting Immunogenic Cell Death and Alleviating Myeloid‐Derived Suppressor Cells by Sono‐Activatable Semiconducting Polymer Nanopartners for …
M Ding, Y Zhang, N Yu, J Zhou, L Zhu… - Advanced …, 2023 - Wiley Online Library
Inducing immunogenic cell death (ICD) by sonodynamic therapy (SDT) is promising for
cancer immunotherapy, which however is inefficient due to oxygen depletion that …
cancer immunotherapy, which however is inefficient due to oxygen depletion that …
Systemic tumor suppression via macrophage‐driven automated homing of metal‐phenolic‐gated nanosponges for metastatic melanoma
Cell‐based therapies comprising the administration of living cells to patients for direct
therapeutic activities have experienced remarkable success in the clinic, of which …
therapeutic activities have experienced remarkable success in the clinic, of which …
Designing drug delivery systems for cell therapy
Cell therapies, such as immune cell and stem cell therapies, are being preclinically and
clinically explored for the treatment of various diseases, but are often limited by low efficacy …
clinically explored for the treatment of various diseases, but are often limited by low efficacy …
Cell–drug conjugates
By combining living cells with therapeutics, cell–drug conjugates can potentiate the
functions of both components, particularly for applications in drug delivery and therapy. The …
functions of both components, particularly for applications in drug delivery and therapy. The …
Prospects for hypoxia-based drug delivery platforms for the elimination of advanced metastatic tumors: from 3D modeling to clinical concepts
M Shahpouri, MA Adili-Aghdam, H Mahmudi… - Journal of Controlled …, 2023 - Elsevier
Hypoxia is a unique characteristic of the solid tumor microenvironment. Hypoxia contributes
to multi-drug resistance, metastasis and cancer relapse through numerous molecular …
to multi-drug resistance, metastasis and cancer relapse through numerous molecular …
Glypican-3-targeted macrophages delivering drug-loaded exosomes offer efficient cytotherapy in mouse models of solid tumours
J Liu, H Zhao, T Gao, X Huang, S Liu, M Liu… - Nature …, 2024 - nature.com
Cytotherapy is a strategy to deliver modified cells to a diseased tissue, but targeting solid
tumours remains challenging. Here we design macrophages, harbouring a surface glypican …
tumours remains challenging. Here we design macrophages, harbouring a surface glypican …
Macrophage-mediated delivery of magnetic nanoparticles for enhanced magnetic resonance imaging and magnetothermal therapy of solid tumors
F Xue, S Zhu, Q Tian, R Qin, Z Wang, G Huang… - Journal of Colloid and …, 2023 - Elsevier
Magnetothermal therapy (MHT) has attracted significant attention due to the advantages of
non-/minimal invasiveness, high efficiency, and excellent tissue penetration. However …
non-/minimal invasiveness, high efficiency, and excellent tissue penetration. However …