Tailoring materials for modulation of macrophage fate

J Li, X Jiang, H Li, M Gelinsky, Z Gu - Advanced Materials, 2021 - Wiley Online Library
Human immune system acts as a pivotal role in the tissue homeostasis and disease
progression. Immunomodulatory biomaterials that can manipulate innate immunity and …

Macrophage cell membrane‐cloaked nanoplatforms for biomedical applications

J Lopes, D Lopes, M Pereira‐Silva, D Peixoto… - Small …, 2022 - Wiley Online Library
Biomimetic approaches utilize natural cell membrane‐derived nanovesicles to camouflage
nanoparticles to circumvent some limitations of nanoscale materials. This emergent cell …

Engineering cells for precision drug delivery: New advances, clinical translation, and emerging strategies

CJ Chao, E Zhang, Z Zhao - Advanced Drug Delivery Reviews, 2023 - Elsevier
Cells have emerged as a promising new form of drug delivery carriers owing to their
distinguished advantages such as naturally bypassing immune recognition, intrinsic …

Augmenting Immunogenic Cell Death and Alleviating Myeloid‐Derived Suppressor Cells by Sono‐Activatable Semiconducting Polymer Nanopartners for …

M Ding, Y Zhang, N Yu, J Zhou, L Zhu… - Advanced …, 2023 - Wiley Online Library
Inducing immunogenic cell death (ICD) by sonodynamic therapy (SDT) is promising for
cancer immunotherapy, which however is inefficient due to oxygen depletion that …

Systemic tumor suppression via macrophage‐driven automated homing of metal‐phenolic‐gated nanosponges for metastatic melanoma

X Liao, G Gong, M Dai, Z **ang, J Pan, X He… - Advanced …, 2023 - Wiley Online Library
Cell‐based therapies comprising the administration of living cells to patients for direct
therapeutic activities have experienced remarkable success in the clinic, of which …

Designing drug delivery systems for cell therapy

LLW Wang, Y Gao, Z Feng, DJ Mooney… - Nature Reviews …, 2024 - nature.com
Cell therapies, such as immune cell and stem cell therapies, are being preclinically and
clinically explored for the treatment of various diseases, but are often limited by low efficacy …

Cell–drug conjugates

Y Wang, J Shi, M **n, AR Kahkoska, J Wang… - Nature Biomedical …, 2024 - nature.com
By combining living cells with therapeutics, cell–drug conjugates can potentiate the
functions of both components, particularly for applications in drug delivery and therapy. The …

Prospects for hypoxia-based drug delivery platforms for the elimination of advanced metastatic tumors: from 3D modeling to clinical concepts

M Shahpouri, MA Adili-Aghdam, H Mahmudi… - Journal of Controlled …, 2023 - Elsevier
Hypoxia is a unique characteristic of the solid tumor microenvironment. Hypoxia contributes
to multi-drug resistance, metastasis and cancer relapse through numerous molecular …

Glypican-3-targeted macrophages delivering drug-loaded exosomes offer efficient cytotherapy in mouse models of solid tumours

J Liu, H Zhao, T Gao, X Huang, S Liu, M Liu… - Nature …, 2024 - nature.com
Cytotherapy is a strategy to deliver modified cells to a diseased tissue, but targeting solid
tumours remains challenging. Here we design macrophages, harbouring a surface glypican …

Macrophage-mediated delivery of magnetic nanoparticles for enhanced magnetic resonance imaging and magnetothermal therapy of solid tumors

F Xue, S Zhu, Q Tian, R Qin, Z Wang, G Huang… - Journal of Colloid and …, 2023 - Elsevier
Magnetothermal therapy (MHT) has attracted significant attention due to the advantages of
non-/minimal invasiveness, high efficiency, and excellent tissue penetration. However …