In mammals, the white adipocyte is a cell type that is specialized for storage of energy (in the
form of triacylglycerols) and for energy mobilization (as fatty acids). White adipocyte …

Lipids are essential metabolites, which function as energy sources, structural components
and signalling mediators. Most cells are able to convert carbohydrates into fatty acids, which …

De novo lipogenesis (DNL) is a complex and highly regulated process in which
carbohydrates from circulation are converted into fatty acids that are then used for …

Background The diminished glucose lowering effect of insulin in obesity, called “insulin
resistance,” is associated with glucose intolerance, type 2 diabetes, and other serious …

Sustained responses to transient environmental stimuli are important for survival. The
mechanisms underlying long-term adaptations to temporary shifts in abiotic factors remain …

Obesity and overweight have increased at an alarming rate in the world during the last three
decades. Obesity is a crucial factor in the development of metabolic abnormalities, including …

Adipose tissue comprises adipocytes and many other cell types that engage in dynamic
crosstalk in a highly innervated and vascularized tissue matrix. Although adipose tissue has …

Global warming is increasingly exacerbating biodiversity loss. Populations locally adapted
to spatially heterogeneous environments may respond differentially to climate change, but …

Human and rodent brown adipose tissues (BAT) appear morphologically and molecularly
different. Here we compare human BAT with both classical brown and brite/beige adipose …

According to Descartes, minds and bodies are distinct kinds of “substance”, and they cannot
have causal interactions. However, in neuroscience, the two-way interaction between the …