Cross-linking mass spectrometry for investigating protein conformations and protein–protein interactions─ a method for all seasons

L Piersimoni, PL Kastritis, C Arlt, A Sinz - Chemical Reviews, 2021 - ACS Publications
Mass spectrometry (MS) has become one of the key technologies of structural biology. In this
review, the contributions of chemical cross-linking combined with mass spectrometry (XL …

Cross-linking mass spectrometry: methods and applications in structural, molecular and systems biology

FJ O'Reilly, J Rappsilber - Nature structural & molecular biology, 2018 - nature.com
Over the past decade, cross-linking mass spectrometry (CLMS) has developed into a robust
and flexible tool that provides medium-resolution structural information. CLMS data provide …

Modular organization and assembly of SWI/SNF family chromatin remodeling complexes

N Mashtalir, AR D'Avino, BC Michel, J Luo, J Pan… - Cell, 2018 - cell.com
Summary Mammalian SWI/SNF (mSWI/SNF) ATP-dependent chromatin remodeling
complexes are multi-subunit molecular machines that play vital roles in regulating genomic …

Cross-linking mass spectrometry (XL-MS): An emerging technology for interactomics and structural biology

C Yu, L Huang - Analytical chemistry, 2017 - pmc.ncbi.nlm.nih.gov
Protein-protein interactions are fundamental to the formation of intricate interaction networks
and the assembly of multisubunit protein complexes that represent the functional …

[HTML][HTML] xiVIEW: Visualisation of crosslinking mass spectrometry data

CW Combe, M Graham, L Kolbowski, L Fischer… - Journal of Molecular …, 2024 - Elsevier
Crosslinking mass spectrometry (MS) has emerged as an important technique for
elucidating the in-solution structures of protein complexes and the topology of protein …

Chemical cross-linking with mass spectrometry: a tool for systems structural biology

JD Chavez, JE Bruce - Current opinion in chemical biology, 2019 - Elsevier
Highlights•Cross-linking-mass spectrometry constitutes a chemical method to produce
protein complex structural model constraints.•A wide range of sample types are applicable …

Interactive peptide spectral annotator: a versatile web-based tool for proteomic applications

DR Brademan, NM Riley, NW Kwiecien… - Molecular & Cellular …, 2019 - ASBMB
Here we present IPSA, an innovative web-based spectrum annotator that visualizes and
characterizes peptide tandem mass spectra. A tool for the scientific community, IPSA can …

Cross-linking/mass spectrometry to get a closer view on protein interaction networks

C Iacobucci, M Götze, A Sinz - Current opinion in biotechnology, 2020 - Elsevier
Just recently, chemical cross-linking combined with mass spectrometry (XL-MS) has
emerged as valuable tool to study protein interaction networks on the system-wide level. The …

xiView: A common platform for the downstream analysis of Crosslinking Mass Spectrometry data

M Graham, C Combe, L Kolbowski, J Rappsilber - BioRxiv, 2019 - biorxiv.org
Abstract xiView provides a common platform for the downstream analysis and visualisation
of Crosslinking Mass Spectrometry data. It is independent of the search software used and …

[HTML][HTML] The interactome of the N-terminus of band 3 regulates red blood cell metabolism and storage quality

A Issaian, A Hay, M Dzieciatkowska, D Roberti… - …, 2021 - ncbi.nlm.nih.gov
Abstract Band 3 (anion exchanger 1; AE1) is the most abundant membrane protein in red
blood cells, which in turn are the most abundant cells in the human body. A compelling …