Multifunctional targetable liposomal drug delivery system in the management of leukemia: Potential, opportunities, and emerging strategies

E Pardhi, R Yadav, A Chaurasiya, J Madan, SK Guru… - Life Sciences, 2023 - Elsevier
The concern impeding the success of chemotherapy in leukemia treatment is descending
efficacy of drugs because of multiple drug resistance (MDR). The previous failure of …

Microcapsules based on biological macromolecules for intestinal health: A review

M Xu, G Feng, J Fang - International Journal of Biological Macromolecules, 2024 - Elsevier
Intestinal dysfunction is becoming increasingly associated with neurological and endocrine
issues, raising concerns about its impact on world health. With the introduction of several …

Mechanisms and barriers in cancer nanomedicine: addressing challenges, looking for solutions

TJ Anchordoquy, Y Barenholz, D Boraschi, M Chorny… - 2017 - ACS Publications
Remarkable progress has recently been made in the synthesis and characterization of
engineered nanoparticles for imaging and treatment of cancers, resulting in several …

Targeted lipid nanoparticles for RNA therapeutics and immunomodulation in leukocytes

N Veiga, Y Diesendruck, D Peer - Advanced Drug Delivery Reviews, 2020 - Elsevier
Abnormalities in leukocytes' function are associated with many immune related disorders,
such as cancer, autoimmunity and susceptibility to infectious diseases. Recent …

Nanomedicine–a promising therapy for hematological malignancies

L Huang, J Huang, J Huang, H Xue, Z Liang… - Biomaterials …, 2020 - pubs.rsc.org
Hematological tumors are a group of diseases defined as the clonal proliferation of blood-
forming cells. In recent years, incidences of hematological malignancies have increased …

Polymeric nanomedicines targeting hematological malignancies

W Gu, R Qu, F Meng, JJLM Cornelissen… - Journal of Controlled …, 2021 - Elsevier
Hematological malignancies (HMs) typically persisting in the blood, lymphoma, and/or bone
marrow invalidate surgery and local treatments clinically used for solid tumors. The …

ImmunoPET imaging of hematological malignancies: From preclinical promise to clinical reality

Y Dun, G Huang, J Liu, W Wei - Drug Discovery Today, 2022 - Elsevier
Immuno-positron emission tomography (immunoPET) imaging is a paradigm-shifting
imaging technique for whole-body and all-lesion tumor detection, based on the combined …

Current progress in non-viral RNAi-based delivery strategies to lymphocytes

S Mizrahy, I Hazan-Halevy, N Dammes… - Molecular Therapy, 2017 - cell.com
RNAi-based therapy holds great promise, as it can be utilized for the treatment of multiple
conditions in an accurate manner via sequence-specific manipulation of gene expression …

Delivery strategies of RNA therapeutics to leukocytes

D Tarab-Ravski, L Stotsky-Oterin, D Peer - Journal of Controlled Release, 2022 - Elsevier
Harnessing RNA-based therapeutics for cancer, inflammation, and viral diseases is
hindered by poor delivery of therapeutic RNA molecules. Targeting leukocytes to treat these …

[HTML][HTML] Rna-loaded nanoparticles for the treatment of hematological cancers

E Garbayo, SH El Moukhtari… - Advanced Drug Delivery …, 2024 - Elsevier
Hematological cancers encompass a diverse group of malignancies affecting the blood,
bone marrow, lymph nodes, and spleen. These disorders present unique challenges due to …