Oxidative stress in the pathophysiology of type 2 diabetes and related complications: Current therapeutics strategies and future perspectives

JS Bhatti, A Sehrawat, J Mishra, IS Sidhu… - Free Radical Biology …, 2022 - Elsevier
Abstract Type 2 diabetes (T2DM) is a persistent metabolic disorder rising rapidly worldwide.
It is characterized by pancreatic insulin resistance and β-cell dysfunction. Hyperglycemia …

Neuropharmacological effects of quercetin: a literature-based review

MS Islam, C Quispe, R Hossain, MT Islam… - Frontiers in …, 2021 - frontiersin.org
Quercetin (QUR) is a natural bioactive flavonoid that has been lately very studied for its
beneficial properties in many pathologies. Its neuroprotective effects have been …

[HTML][HTML] Nrf2: An all-rounder in depression

C Zuo, H Cao, Y Song, Z Gu, Y Huang, Y Yang, J Miao… - Redox biology, 2022 - Elsevier
The balance between oxidation and antioxidant is crucial for maintaining homeostasis. Once
disrupted, it can lead to various pathological outcomes and diseases, such as depression …

Antioxidant activity of Citrus fruits

Z Zou, W **, Y Hu, C Nie, Z Zhou - Food chemistry, 2016 - Elsevier
Citrus is well-known for its nutrition and health-promotion values. This reputation is derived
from the studies on the biological functions of phytochemicals in Citrus fruits and their …

[HTML][HTML] Caffeine and its antioxidant properties—it is all about dose and source

BE Ősz, G Jîtcă, RE Ștefănescu, A Pușcaș… - International journal of …, 2022 - mdpi.com
Caffeine is the most frequently used substance with a central nervous system stimulant
effect, but its consumption is most often due to the intake of foods and drinks that contain it …

Mechanisms of neuroprotection by quercetin: counteracting oxidative stress and more

LG Costa, JM Garrick, PJ Roquè… - Oxidative medicine and …, 2016 - Wiley Online Library
Increasing interest has recently focused on determining whether several natural
compounds, collectively referred to as nutraceuticals, may exert neuroprotective actions in …

Evaluating the antioxidant capacity of natural products: A review on chemical and cellular-based assays

C López-Alarcón, A Denicola - Analytica chimica acta, 2013 - Elsevier
Oxidative stress is associated with several pathologies like cardiovascular,
neurodegenerative, cancer and even aging. It has been suggested that a diet rich in …

Neuroprotective potentials of flavonoids: Experimental studies and mechanisms of action

P Bellavite - Antioxidants, 2023 - mdpi.com
Neurological and neurodegenerative diseases, particularly those related to aging, are on
the rise, but drug therapies are rarely curative. Functional disorders and the organic …

Molecular targets underlying the anticancer effects of quercetin: an update

F Khan, K Niaz, F Maqbool, F Ismail Hassan… - Nutrients, 2016 - mdpi.com
Quercetin, a medicinally important member of the flavonoid family, is one of the most
prominent dietary antioxidants. It is present in a variety of foods—including fruits, vegetables …

Bioactive effects of quercetin in the central nervous system: Focusing on the mechanisms of actions

N Suganthy, KP Devi, SF Nabavi, N Braidy… - Biomedicine & …, 2016 - Elsevier
Quercetin, a ubiquitous flavonoid that is widely distributed in plants is classified as a
cognitive enhancer in traditional and oriental medicine. The protective effects of quercetin for …