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Targeting the RAS/RAF/MAPK pathway for cancer therapy: from mechanism to clinical studies
ME Bahar, HJ Kim, DR Kim - Signal transduction and targeted therapy, 2023 - nature.com
Metastatic dissemination of solid tumors, a leading cause of cancer-related mortality,
underscores the urgent need for enhanced insights into the molecular and cellular …
underscores the urgent need for enhanced insights into the molecular and cellular …
Non-coding RNA in cancer drug resistance: underlying mechanisms and clinical applications
X Zhou, X Ao, Z Jia, Y Li, S Kuang, C Du… - Frontiers in …, 2022 - frontiersin.org
Cancer is one of the most frequently diagnosed malignant diseases worldwide, posing a
serious, long-term threat to patients' health and life. Systemic chemotherapy remains the first …
serious, long-term threat to patients' health and life. Systemic chemotherapy remains the first …
Exosomal circRNAs in cancer: implications for therapy resistance and biomarkers
Z Lin, Y Ji, J Zhou, G Li, Y Wu, W Liu, Z Li, T Liu - Cancer Letters, 2023 - Elsevier
Despite the advances in cancer treatment in recent years, the development of resistance to
cancer therapy remains the biggest hurdle towards curative cancer treatments. Therefore …
cancer therapy remains the biggest hurdle towards curative cancer treatments. Therefore …
Humanin and its pathophysiological roles in aging: A systematic review
D Coradduzza, A Congiargiu, Z Chen, S Cruciani… - Biology, 2023 - mdpi.com
Simple Summary Humanin is a small mitochondrial-derived peptide still under study, with a
number of potential therapeutic applications for various age-related diseases. It plays an …
number of potential therapeutic applications for various age-related diseases. It plays an …
The role of lncRNA NEAT1 in human cancer chemoresistance
F Long, X Li, J Pan, H Ye, C Di, Y Huang, J Li… - Cancer Cell …, 2024 - Springer
Chemotherapy is currently one of the most effective methods in clinical cancer treatment.
However, chemotherapy resistance is an important reason for poor chemotherapy efficacy …
However, chemotherapy resistance is an important reason for poor chemotherapy efficacy …
Enzymatically crosslinked magnetic starch-grafted poly (tannic acid) hydrogel for “smart” cancer treatment: an in vitro chemo/hyperthermia therapy study
A novel strategy was designed and developed based of horseradish peroxidase (HRP)-
mediated crosslinking of tyramine-functionalized starch (Tyr-St), tannic acid (TA) and …
mediated crosslinking of tyramine-functionalized starch (Tyr-St), tannic acid (TA) and …
Recent update and drug target in molecular and pharmacological insights into autophagy modulation in cancer treatment and future progress
Recent evidence suggests that autophagy is a governed catabolic framework enabling the
recycling of nutrients from injured organelles and other cellular constituents via a lysosomal …
recycling of nutrients from injured organelles and other cellular constituents via a lysosomal …
Proton sponge nanocomposites for synergistic tumor elimination via autophagy inhibition-promoted cell apoptosis and macrophage repolarization-enhanced immune …
Y Duan, W Zhang, Y Ouyang, Q Yang… - … Applied Materials & …, 2024 - ACS Publications
Cytoprotective autophagy and an immunosuppressive tumor microenvironment (TME) are
two positive promoters for tumor proliferation and metastasis that severely hinder therapeutic …
two positive promoters for tumor proliferation and metastasis that severely hinder therapeutic …
Mitochondrial signaling pathways and their role in cancer drug resistance
Mitochondria, traditionally known as cellular powerhouses, now emerge as critical signaling
centers influencing cancer progression and drug resistance. The review highlights the role …
centers influencing cancer progression and drug resistance. The review highlights the role …
Exposure to select PFAS and PFAS mixtures alters response to platinum-based chemotherapy in endometrial cancer cell lines
Background Exposure to per-and poly-fluoroalkyl substances (PFAS) has been associated
with significant alterations in female reproductive health. These include changes in …
with significant alterations in female reproductive health. These include changes in …