The ability of the brain to store and process information relies on changing the strength of
connections between neurons. Synaptic facilitation is a form of short-term plasticity that …

▪ Abstract Synaptic transmission is a dynamic process. Postsynaptic responses wax and
wane as presynaptic activity evolves. This prominent characteristic of chemical synaptic …

Different types of synapses are specialized to interpret spike trains in their own way by virtue
of the complement of short-term synaptic plasticity mechanisms they possess. Numerous …

THE mammalian pancreas is a mixed exocrine and endocrine gland that, in most species,
arises from ventral and dorsal buds which subsequently merge to form the pancreas. In both …

Taking a step-by-step approach to modelling neurons and neural circuitry, this textbook
teaches students how to use computational techniques to understand the nervous system at …

Measles virus continues to be a major killer of children, claiming roughly one million lives a
year. Measles virus infection causes profound immunosuppression, which makes measles …

Synapse,” intended to contrast our grasp of presynaptic Angleson and Betz (1997) quite
recently reviewed in physiology with our understanding of postsynaptic detail techniques for …

Calcium-triggered fusion of synaptic vesicles and neurotransmitter release are fundamental
signalling steps in the central nervous system. It is generally assumed that fast transmitter …

Calcium signaling underlies much of physiology. Almost all the Ca2+ in the cytoplasm is
bound to buffers, with typically only∼ 1% being freely ionized at resting levels in most cells …

Markov kinetic models were used to synthesize a complete description of synaptic
transmission, including opening of voltage-dependent channels in the presynaptic terminal …